眼角膜深层异物伤的急诊处置及治疗体会

Emergency Management and Treatment Insights for Deep Foreign Body Injuries of the Cornea

目的分析急诊治疗眼角膜深层异物伤的治疗方法及疗效,为临床治疗提供指导。方法收集2021年1月至2024年1月银川进川眼科医院收治的82例眼角膜深层异物伤患者资料,根据术后是否给予重组人表皮生长因子(EGF)进行治疗分为观察组和对照组。比较两组的临床疗效、角膜愈合和住院时间、并发症发生情况。结果观察组治愈率(67.44%)、有效率(97.67%)显著高于对照组(32.56%,79.07%),差异具有统计学意义(P<0.05)。观察组角膜愈合时间、住院时间均显著短于对照组(P<0.001)。观察组并发症发生率(4.65%)显著低于对照组(20.93%),差异有统计学意义(P<0.05)。结论对于眼角膜深层异物伤患者,急诊手术剔除角膜深层异物后,使用左氧氟沙星联合EGF滴眼液,不仅可提高患者的临床疗效,还能缩短创面愈合时间和住院时间,降低并发症的发生率。

Objective To analyze the treatment methods and efficacy of deep corneal foreign body injury in emergency treatment,and provide guidance for clinical treatment.Methods The data of 82 patients with corneal deep foreign body injury admitted to Yinchuan Jinchuan Eye Hospital from January 2021 to January 2024 were collected.According to whether recombinant human epidermal growth factor(EGF)was given after surgery,they were divided into an observation group and a control group.The clinical efficacy,corneal healing,hospitalization time,and complications of the two groups were compared.Results The cure rate(67.44%)and effective rate(97.67%)in the observation group were significantly higher than those in the control group(32.56%,79.07%),and the difference was statistically significant(P<0.05).The corneal healing time and hospitalization time in the observation group were significantly shorter than those in the control group(P<0.001).The incidence of complications in the observation group(4.65%)was significantly lower than that in the control group(20.93%),and the difference was statistically significant(P<0.05).Conclusion For patients with deep corneal foreign body injury,emergency surgery to remove the foreign body in the deep cornea followed by levofloxacin combined with EGF eye drops can not only improve the clinical efficacy of the patient,but also shorten the wound healing time and hospitalization time,and reduce the incidence of complications.