摘要
目的:为枸杞子质量评价模式的构成提供思路,奠定基础。方法:基于近年来的文献资料,对枸杞子的化学成分、质量影响因素、现有标准及质量评价模式研究进展等梳理归纳。结果与结论:枸杞子活性成分种类复杂,包括枸杞多糖、类胡萝卜素、黄酮和维生素等,质量受产地、品种、种植加工方式等因素的影响。枸杞子药典标准主要以甜菜碱和枸杞多糖作为质控指标,而现有商品规格等级划分中主要以枸杞子果粒大小作为评价依据,均具有一定的局限性。现已有的枸杞子质量评价研究通过灰色关联度分析法、层次分析法和判别分析法等探索枸杞子多个质量参数的权重系数,进而建立质量评价模型,对枸杞子质量进行综合评分。为建立科学、统一的枸杞子质量评价标准提供思路。
Objective:To provide ideas and lay the foundation for the composition of quality evaluation model of Lycium barbarum L..Methods:Based on the literature in recent years,the chemical composition,quality influencing factors,existing standards and the research progress of quality evaluation model of L.barbarum L.were reviewed and summarized.Results and Conclusion:The types of active ingredients of L.barbarum L.were complex,including lycium barbarum polysaccharides,carotenoids,flavonoids and vitamins,etc.,and the quality was affected by factors such as place of origin,species,planting and processing methods.The pharmacopoeia standard of L.barbarum L.mainly uses betaine and lycium barbarum polysaccharide as quality control indicators,while the existing commodity specification grade division mainly uses the fruit size as the evaluation basis,which has certain limitations.The existing researches on quality evaluation of L.barbarum L.explored the weight coefficients of multiple quality parameters of L.barbarum L.through gray correlation analysis,hierarchical analysis and discriminant analysis,etc.,and then established a quality evaluation model to score the quality of L.barbarum L.comprehensively.Provide ideas for the establishment of scientific and unified quality evaluation standard of L.barbarum L..
作者
罗群
王莹
李耀磊
刘芫汐
王丹丹
金红宇
马双成
魏锋
Luo Qun;Wang Ying;Li Yaolei;Liu Yuanxi;Wang Dandan;Jin Hongyu;Ma Shuangcheng;Wei Feng(Shenyang Pharmaceutical University,Shenyang 117004,China;National Institutes for Food and Drug Control,Beijing 102629,China;Chiness Pharmacopoe ia Committee,Beijing 100061,China)
出处
《中国药事》
CAS
2024年第11期1323-1337,共15页
Chinese Pharmaceutical Affairs
基金
国家自然基金委员会青年基金项目(编号82204617)
国家重点研发计划项目(编号2022YFC3501505)。
关键词
枸杞子
化学成分
质量评价
等级划分
多糖
Lycium barbarum L.
chemical composition
quality evaluation
grade division
polysaccharides