采血时残留手消对血常规分析的影响

The effect of residual hand sanitizer on complete blood count analysis

目的:探究爱护佳免洗手消毒液(简称手消)对血常规分析的影响。方法:随机选取2022年4月在南通大学附属医院进行血常规检测的标本54例,各取180μL分别加入0、6、15、30μL手消中,观察在不同浓度下,手消对血常规检测不同指标的影响。结果:与未加手消相比,当手消量为6μL时,嗜酸性粒细胞增高,血红蛋白降低(P<0.05)。当手消量为15μL时,红细胞平均血红蛋白、红细胞分布宽度、红细胞平均体积增高,淋巴细胞、中性粒细胞、单核细胞、RBC减少(均P<0.05)。当手消量增至30μL时,上述指标变化趋势相同,同时平均血小板体积、血小板分布宽度增高,嗜碱性粒细胞、红细胞平均血红蛋白浓度降低(均P<0.05)。结论:手消影响血常规分析检测结果,在采血过程中尤其是婴幼儿末梢采血时应注意手消的正确使用,避免因手消污染导致测定结果出现误差。

Objective:To explore the effect of Avagard rinse-free hand sanitizer(hand sanitizer)on complete blood count analysis.Methods:Fifty-four samples were randomly selected for complete blood count in Affiliated Hospital of Nantong University at April 2022.180μL of samples was added into 0,6,15,30μL of hand sanitizer to observe the effect on various quotas of complete blood count detection.Results:The experimental results indicated that eosinophil increased and hemoglobin decreased at 6μL of added hand sanitizer compared with control group(all P<0.05).When the amount of added hand sanitizer got to 15μL,mean corpuscular hemoglobin,red cell distribution width and mean corpuscular volume all increased,lymphocyte,neutrophil,monocyte and RBC decreased(all P<0.05).When the amount of added hand sanitizer got to 30μL,the above indicators followed the same trend.Meanwhile,mean platelet volume and platelet distribution width increased,Basophil and mean corpuscular hemoglobin cincentration decreased(all P<0.05).Conclusion:The hand sanitizer could influence complete blood count analytical results.In order to avoid detected errors because of pollution,the right use of hand sanitizer should be careful in blood collection procedure,particularly in the peripheral blood collection of infant.