穴位埋线联合炔雌醇环丙孕酮片治疗多囊卵巢综合征的临床疗效

Clinical Efficacy of Acupoint Embedding Combined with Ethinylestradiol and Cyproterone Acetate Tablets in the Treatment of Polycystic Ovary Syndrome

目的:分析穴位埋线联合炔雌醇环丙孕酮片治疗多囊卵巢综合征的临床疗效。方法:按照随机数字表法将安阳市妇幼保健院2023年4月至2023年12月期间收治的多囊卵巢综合征患者100例分为对照组与观察组,分别为50例。对照组患者实施炔雌醇环丙孕酮片治疗,观察组患者实施穴位埋线联合炔雌醇环丙孕酮片治疗,两组患者均治疗3个月。比较两组患者经过临床治疗后总有效率,治疗前后空腹血糖(FPG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)、稳态模型胰岛素抵抗指数(HOMA–IR),治疗前及治疗3个月后周期排卵率、身体质量指数(BMI),治疗前后血清黄体生成激素(LH)、睾酮(T)、卵泡刺激素(FSH)水平。结果:观察组患者治疗总有效率为80.00%(40/50),相较于对照组的62.00%(31/50)更高,差异具有统计学意义(P <0.05);治疗后观察组患者外周血FPG、HbA1c、FINS、HOMA–IR水平相较于对照组更低,差异具有统计学意义(P <0.05);治疗后观察组患者排卵率相较于对照组更高,BMI相较于对照组更低,差异具有统计学意义(P <0.05);治疗后观察组患者血清LH、T、FSH水平、LH/FSH比值相较于对照组更低,差异具有统计学意义(P <0.05)。结论:多囊卵巢综合征患者采用穴位埋线联合炔雌醇环丙孕酮片治疗可进一步提升疗效,调节糖脂代谢水平、胰岛素抵抗、激素水平,提高排卵率,降低BMI。

Objective To analyze the clinical efficacy of acupoint embedding combined with ethinylestradiol and cyproterone acetate tablets in the treatment of polycystic ovary syndrome.Methods A total of 100 patients with polycystic ovary syndrome admitted to Anyang Maternal and Child Health Care Hospital from April 2023 to December 2023 were randomly divided into a control group and an observation group,with 50 cases in each group.Patients in the control group were treated with ethinylestradiol and cyproterone acetate tablets,while patients in the observation group were treated with acupoint embedding combined with ethinylestradiol and cyproterone acetate tablets.Both groups were treated for 3 months.The total effective rate after clinical treatment,fasting plasma glucose(FPG),glycosylated hemoglobin(HbA1c),fasting insulin(FINS),and homeostasis model assessment of insulin resistance(HOMA-IR)before and after treatment,ovulation rate,body mass index(BMI)before and 3 mouths after treatment, and levels of serum luteinizing hormone (LH), testosterone (T), and follicle-stimulating hormone (FSH) before and after treatment were compared between the two groups. Results The total effective rate of treatment in the observation group was 80.00% (40/50), which was higher than 62.00% (31/50) in the control group, and the difference was statistically significant (P < 0.05). After treatment, the levels of FPG, HbA1c, FINS, and HOMA-IR in the observation group were lower than those in the control group, and the differences were statistically significant (P < 0.05). After treatment, the ovulation rate in the observation group was higher than that in the control group, and the BMI was lower than that in the control group, with statistically significant differences (P < 0.05). After treatment, the levels of serum LH, T, FSH, and LH/FSH in the observation group were lower than those in the control group, and the differences were statistically significant (P < 0.05). Conclusion The use of acupoint embedding combined with ethinylestradiol and cyproterone acetate tables in the treatment of patients with polycystic ovary syndrome can further improve the efficacy, regulate the levels of glucose and lipid metabolism, insulin resistance, and hormone levels, increase the ovulation rate, and reduce the BMI.