支气管动脉栓塞介入治疗术在急性咯血治疗中的应用价值

The Application Value of Bronchial Artery Embolization Interventional Therapy in the Treatment of Acute Hemoptysis

目的:探讨支气管动脉栓塞介入治疗术在急性咯血患者治疗中的可行性。方法:选取2019年4月至2023年4月期间高安市人民医院收治的100例急性咯血患者,采用随机数表法分为对照组与观察组,各50例。对照组给予内科药物治疗,观察组给予支气管动脉栓塞介入治疗术治疗。对两组患者治疗前后的咯血量、各项凝血指标、临床疗效和不良反应进行比较。结果:治疗前两组患者的咯血量、血浆纤维蛋白原(FIB)水平、凝血酶原时间(PT)、血小板计数(PLT)比较,差异无统计学意义(P>0.05),治疗3 d、5 d、7 d后观察组患者的咯血量均低于对照组,治疗7 d后观察组患者的血浆FIB水平、PLT高于对照组,PT低于对照组,治疗7 d后观察组患者的临床总有效率为94.00%,高于对照组的40.00%,差异均具有统计学意义(P<0.05)。观察组不良反应总发生率为12.00%,与对照组的18.00%比较,差异无统计学意义(P>0.05)。结论:支气管动脉栓塞介入治疗术治疗急性咯血能够快速减少咯血量,改善凝血功能及临床疗效,且无明显不良反应。

Objective To explore the feasibility of bronchial artery embolization intervention in the treatment of acute hemoptysis patients.Methods A total of 100 patients with acute hemoptysis admitted to Gao'an People's Hospital from April 2019 to April 2023 were randomly divided into a control group and an observation group using a random number table method,with 50 patients in each group.The control group was treated with internal medicine,while the observation group was treated with bronchial artery embolization intervention therapy.The hemoptysis volume,coagulation index,clinical efficacy,and adverse reactions of two groups of patients were compared before and after treatment.Results Before treatment,there was no statistically significant difference between the two groups in terms of hemoptysis volume,the levels of plasma fibrinogen(FIB),prothrombin time(PT),and platelet count(PLT)(P>0.05).After 3,5 and 7 days of treatment,the hemoptysis volume of the observation group was lower than that of the control group.After 7 days of treatment,the levels of plasma FIB and PLT in the observation group were higher than those in the control group,while PT was lower than that of the control group.After 7 days of treatment,the total clinical effective rate of the observation group was 94.00%,higher than 40.00%of the control group,the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was 12.00%,and there was no significant difference compared to 18.00%in the control group(P>0.05).Conclusion Bronchial artery embolization intervention therapy for acute hemoptysis can quickly reduce the amount of hemoptysis,improve coagulation function,and clinical efficacy,without significant adverse reactions.