既往新型冠状病毒感染患者行胸腔镜下肺部手术预后的比较研究

A Comparative Study of the Prognosis of Patients UndergoingThoracoscopic Lung Surgery with a History of SARS-CoV-2 Infection

目的研究既往新型冠状病毒感染患者行胸腔镜下肺部手术的预后及住院时间的影响因素。方法选择首都医科大学电力教学医院2022年7月至2023年4月择期行胸腔镜下肺部手术患者的临床信息资料进行回顾性比较研究。根据患者既往病史中是否感染新型冠状病毒分为2组,即感染组和非感染组。比较2组患者的一般资料、手术资料和临床结局,分析影响既往新型冠状病毒感染患者住院时间的危险因素。结果有198例患者纳入本研究,感染组97例,非感染组101例。2组患者一般资料、手术资料、术后ICU的入住率、术后死亡率、术后住院时间比较差异无统计学意义(P>0.05)。2组患者术后最常见的并发症是呼吸道感染,但比较差异无统计学意义(P>0.05)。多因素Logistic回归分析结果显示,各变量之间不存在共线性(均VIF<10),肺部并发症是影响术后住院时间的独立危险因素。结论既往新型冠状病毒感染患者痊愈8周后行胸腔镜下肺部手术不影响手术效果,不增加术后并发症。影响术后住院时间的因素是肺部并发症。

Objective To investigate the clinical characteristics and factors affecting prognosis in patients with a history of SARS-CoV-2 infection undergoing pulmonary surgery.Methods A retrospective comparative study was conducted on the clinical information of patients who underwent elective thoracoscopic lung surgery at the Capital Medical University Power Teaching Hospital from July 2022 to April 2023.According to whether the patients were infected with SARS-CoV-2 in their past medical history,all the cases were divided into two groups:the SARS-CoV-2 infection group and the SARS-CoV-2 non-infection group.Compare the general information,surgical data,and clinical outcomes of the two groups of patients,and analyze the risk factors that affect the length of hospitalization for patients with previous novel coronavirus infection.Results There were 198 patients included in this study,97 in the infected group and 101 in the non-infected group.There was no significant difference in general information,surgical data,postoperative ICU admission rate,postoperative mortality,and postoperative hospitalization time between the two groups of patients(P>0.05).The most common postoperative complication was respiratory tract infection,but the difference was not statistically significant(P>0.05).Multiple logistic regression analysis showed that there was no collinearity among all variables(VIF<10),and pulmonary complications were an independent risk factor for postoperative hospital stay.Conclusion Thoracoscopic lung surgery performed 8 weeks after recovery from SARS-CoV-2 infection does not affect surgical outcomes,nor does it increase the incidence of postoperative complications.The primary factor influencing postoperative hospital stay was pulmonary complications.