非小细胞肺癌患者胸腔镜下肺癌根治术后发生ICU综合征的影响因素分析

Analysis of Influencing Factors of ICU Syndrome in Patients with Non-small Cell Lung Cancer after Thoracoscopic Radical Lung Cancer Surger

目的:分析非小细胞肺癌(NSCLC)患者胸腔镜下肺癌根治术后发生ICU综合征的影响因素。方法:收集2021年1月—2024年2月于汕头大学医学院附属肿瘤医院行胸腔镜下肺癌根治术且术后入住ICU的86例NSCLC患者的临床资料,按照是否发生ICU综合征分为观察组(发生ICU综合征)与对照组(未发生ICU综合征)。对比两组临床资料差异,采用多因素Logistic回归分析NSCLC患者根治术后发生ICU综合征的影响因素。结果:86例患者中33例发生ICU综合征,占比38.37%。观察组年龄≥60岁、文化程度为初中及以下、家庭月收入<4500元、入住ICU时间>3 d、采用呼吸机治疗、术后2 d使用约束带、曲马多日均使用量>100 mg占比均高于对照组(P<0.05)。多因素Logistic回归分析显示,年龄≥60岁、术后2 d使用约束带、曲马多日均使用量>100 mg均是NSCLC患者术后发生ICU综合征的独立危险因素。结论:NSCLC患者术后ICU综合征发生率较高,年龄≥60岁、术后2 d使用约束带、曲马多日均使用量>100 mg是其独立危险因素,应根据上述因素进行预防性护理。

Objective:To analyze the influencing factors of ICU syndrome in patients with non-small cell lung cancer(NSCLC)after thoracoscopic radical lung cancer.Methods:Clinical data of eighty-sixNSCLCpatients admitted to ICU after thoracoscopic radical resection of lung cancer in the Affiliated Cancer Hospital of Shantou University Medical School from January2021 to February 2024 were collected.They were divided into observation group(ICU syndrome)and control group(no ICU syndrome)according to whether ICU syndrome occurred.By comparing the difference of clinical data between the two groups,multivariate Logistic regression was used to analyze the influencing factors of ICUsyndrome in NSCLC patients after radical surgery.Results:ICUsyndrome occurred in 33 of the 86 patients,accounting for 38.37%;the age of observation group was≥60 years old,the education level was junior high school or below,the monthly family income was<4500 yuan,the time of ICU stay>3 days,the use of ventilator,the use of restraint band 2 days after surgery,and the proportion of tramal daily use>100 mg were higher than those of control group(P<0.05).Multivariate Logistic regression analysis showed that age≥60 years,use of restraint band 2 days after surgery,tramadol daily use>100mg were independent risk factors for postoperative ICUsyndrome in NSCLC patients(P<0.05).Conclusion:Patients with NSCLC have a high incidence of ICU syndrome after surgery.Age≥60 years old,use of restraint band 2 days after surgery,and tramadol daily dose>100 mg are independent risk factors,and preventive care should be conducted according to the above factors.