Changes in FOXO1 expression in β-cells during the progression of type 2 diabetes mellitus and aging

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摘要 Objective To investigate the changes of β-cell dedifferentiation in type 2 diabetes mellitus(T2DM) and aging subjects.Methods Using pancreatic samples from 12 prediabetic individuals,21 type 2 diabetic patients,and 27 control,the level of β-cell dedifferentiation was assessed by immunofluorescence staining for FOXO1 and insulin expression.

作者 LIANG Rui 梁瑞(NHC Critical Care Med Key Lab,Tianjin 1st Centr Hosp,Tianjin 300384,China)

机构地区 NHC Critical Care Med Key Lab

出处《China Medical Abstracts(Internal Medicine)》 2024年第3期158-159,共2页 中国医学文摘（内科学分册英文版）

关键词 FOXO1 expression. MELLITUS

分类号 R58 [医药卫生—内分泌]

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China Medical Abstracts(Internal Medicine)

2024年第3期

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Changes in FOXO1 expression in β-cells during the progression of type 2 diabetes mellitus and aging

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