中药祛疣煎剂配合二氧化碳激光和重组人干扰素外用治疗外阴肛门尖锐湿疣的效果分析

Clinical Observation on the Therapeutic Effect of Combination of Traditional Chinese Medicine and Western Medicine on Genital Condyloma Acuminatum

目的分析中药祛疣煎剂配合二氧化碳激光和重组人干扰素外用治疗外阴肛门尖锐湿疣的效果。方法将90例外阴肛门尖锐湿疣患者随机分为实验组和对照组,每组45例。对照组采用二氧化碳激光加重组人干扰素凝胶外用治疗,实验组在对照组治疗的基础上加用祛疣煎剂治疗。治疗3个月后随访,统计治愈率和复发率。结果90例患者实际完成实验72例,其中实验组38例,对照组35例;实验组治愈率71.1%、复发率28.9%,对照组治愈率37.1%、复发率62.9%,复发率实验组明显低于对照组,治愈率实验组明显高于对照组,差异具有统计学意义(P<0.01);1个疗程治疗费用对照组为3000元以内,实验组为4500元以内,其中中药制剂费用在1500元左右;实验组和对照组均未出现明显的药物过敏及胃肠道反应。结论二氧化碳激光治疗联合重组人干扰素外用和中药祛疣煎剂内服外用对尖锐湿疣治疗和防复发的效果要优于单纯使用二氧化激光治疗联合重组人干扰素外用的方法,且整体方案价格适中,值得在基层医院推广。

Objective To analyse the effect of Chinese herbal decoction with combination of carbon dioxide laser and interferon for the treatment of recurrent condyloma acuminatum on vulva and anus Method We selected 90 condyloma acuminatum patients from dermatology of Chang-zhou Wujing Chinese medicine hospital and divided them into two groups randomly,45 patients were study group and the others were control group.To the control treatment group,we applied the therapies of carbon dioxide laser and external using interferon.Meanwhile,the experimental treatment group would apply Chinese herbal decoction based on the therapies used by the control group for the treatment of recurrent condyloma acuminatum.We would do some research on cure rate and recurrence rate 3 months later.Result There are 72 patients has completed this experi-ment among the 90 subjects,38 from the experimental group,35 from controlled group.the cure rate of experiment group is 71.1%and the recurrence rate is 28.9%,meanwhile,the cure rate of control group is 37.1%and the recurrence rate is 62.9%.It`s obviously that the experiment group has much higher cure rate and lower recurrence rate than the study group,that means the result obviously match statistical significance(P<0.01);A course of treatment cost 3000 CNY in experi-mental group and 4500 CNY in control group(Including 1500 for Chinese herbal medicine);in ad-dition,none of these two groups`patients appeared anaphylactic reaction and gastrointestinal reac-tion Conclusion the effect of Chinese medicine combining with carbon dioxide laser and interfer-on to cure vulva and anus condyloma acuminate is superior to carbon dioxide laser and interfer-on only.from the aspect of pharmaceutical economics,Chinese medicine combines with carbon di-oxide laser and interferon is worth to be generalized to primary hospital.