中医药治疗IgA肾病研究进展

Research Progress of Traditional Chinese Medicine Treatment of IgA Nephropathy

IgA肾病是最为常见的一种原发性肾小球疾病,以血尿、不同程度蛋白尿、高血压、水肿及肾功能的损伤为主要临床表现,以肾小球系膜区出现IgA或IgA为主的免疫球蛋白弥漫性沉积为主要病理特点。由于目前其发病机制尚未阐明,西医多以基础治疗和对症治疗为主,尚无理想的治疗手段。经过长时间临床实践发现,中医药治疗IgA肾病在缓解患者症状、改善预后、提高自身抗病能力方面展现出独特优势。辨证论治是中医药治疗的基本原则,其根据患者症状及患病阶段,强调“辨病”和“辨证”相结合,分期分型诊疗IgA肾病,为患者提供更加全面、个性化的治疗选择,从而为临床提供参考。

IgA nephropathy is the most common primary glomerular disease,with hematuria,different degrees of proteinuria,hypertension,edema and renal function injury as the main clinical manifestations,and the diffuse deposition of IgA or IgA predominant immunoglobulin in the mesangial area as the main pathological features.Because its pathogenesis has not been clarified at present,western medicine mainly focuses on basic treatment and symptomatic treatment,and there is no ideal treatment method.After a long period of clinical practice,it is found that the treatment of IgA nephropathy with traditional Chinese medicine(TCM)has shown unique advantages in alleviating patients′symptoms,improving their prognosis and improving their own disease resistance.Diagnosis and treatment based on syndrome differentiation is the basic principle of TCM treatment.It emphasizes the combination of"disease differentiation"and"syndrome differentiation"according to the patient′s symptoms and stage of illness,and diagnoses and treats IgA nephropathy by stages and types,providing the patients with more comprehensive and individualized treatment choices,and thus providing reference for the clinical practice.