刘氏小儿推拿联合乳糖酶治疗儿童腹泻继发乳糖不耐受的疗效观察

The Efficacy of Massage combined with Lactase in the Treatment of Diarrhoea Secondary to Lactose Intolerance in Children

目的:观察刘氏小儿推拿联合口服乳糖酶治疗儿童腹泻继发乳糖不耐受的临床疗效。方法:将60例腹泻继发乳糖不耐受患儿按随机数字表法分为对照组和治疗组,每组30例,对照组患儿予以口服乳糖酶治疗,治疗组在对照组基础上予以刘氏小儿推拿治疗,两组治疗周期均为2周。比较两组患儿主要症状(主症)积分(大便次数、大便性状、总积分)、次要症状(次症)积分(精神状态、肛周红肿、小便情况、腹胀、总积分)、临床总有效率、尿半乳糖酶转阴率及不良反应。结果:治疗组有效率为96.67%(29/30),对照组总有效率为90.00%(27/30),两组比较,差异无统计学意义(P>0.05)。两组患儿大便次数、大便性状、主症总积分、精神状态、腹胀、肛周红肿、小便情况及次症总积分均低于治疗前(P<0.05),且治疗组患儿治疗后大便次数、大便性状、主症总积分、腹胀、肛周红肿、小便情况及次症总积分低于对照组(P<0.05)。两组患儿治疗后精神状态评分比较,差异无统计学意义(P>0.05)。治疗组尿半乳糖酶转阴率为93.33%(28/30),对照组尿半乳糖酶转阴率为56.67%(17/30),治疗组尿半乳糖酶转阴率高于对照组(P<0.01)。两组均未发现明显不良反应。结论:刘氏小儿推拿联合乳糖酶能有效改善腹泻继发乳糖不耐受患儿临床症状,提高患儿尿半乳糖酶的转阴率,且无不良反应。

Objective:To observe the clinical efficacy of Liu's paediatric massage combined with lactase in the treatment of children with diarrhea secondary to lactose intolerance.Methods:A total of 60 children with diarrhoea secondary to lactose intolerance were divided into a control group and an observation group according to the method of random number table,with 30 cases in each group;the control group was treated with oral lactase,and the observation group was treated with Liu's paediatric massage on the basis of the control group,and the treatment cycle was 2 weeks.The children's primary symptom scores(stool frequency,stool characteristics,total scores),secondary symptom scores(mental state,perianal,urine volume,abdominal distension,total scores),the overall clinical effectiveness rate,urinary galactosidase conversion rate and adverse reactions were compared of the two groups.Results:The effective rate of the observation group was 96.67%(29/30),the total effective rate of the control group was 90.00%(27/30),and there was no significant difference between the two groups(P>0.05).The stool frequency,stool properties,total primary symptom scores,mental status,abdominal distension,perianal redness and swelling,urination and total secondary symptom scores of the children in both groups were lower than those before treatment(P<0.05),and the above scores of the observation group,except for the mental state score,were lower than those of the control group(P<0.05).There was no significant difference between the two groups of children in terms of their mental status(P>0.05).The conversion rate of urinary galactokinase in the observation group was 93.33%(28/30),and the conversion rate of urinary galactokinase in the control group was 56.67%(17/30),which was significantly higher in the observation group than in the control group(P<0.01).No adverse reactions occurred in both groups.Conclusions:Liu's paediatric massage combined with lactase can effectively improve the clinical symptoms of children with diarrhoea secondary to lactose intolerance,increase the conversion rate of urinary galactase,and have no adverse effects.