茵陈蒿汤外洗及光疗早期干预治疗新生儿高胆红素血症的临床效果

Clinical effect of external washing with Yinchenhao Tang and early intervention with phototherapy in the treatment of neonatal hyperbilirubinemia

目的探讨茵陈蒿汤外洗及光疗早期干预治疗新生儿高胆红素血症的临床效果。方法选取柳州市中医医院产科2020年7月至2023年6月出生的新生儿中新生儿黄疸1643例,予13味茵陈蒿汤熏洗,诊断为新生儿高胆红素血症499例(30.37%),将其按照患儿接受的治疗方法不同分成三组。A组168例:为光疗+中药洗浴组,B组177例:为中药洗浴组,C组154例:为光疗组。通过收集三组母婴基本信息等临床资料,建立数据库,统计分析并比较三组疗效。结果B组的黄疸消退时间、治疗后血清总胆红素值高于A组与C组,差异有统计学意义(P<0.05)。A组的光疗时间、住院时间短于C组,差异有统计学意义(P<0.05)。结论早期予13味茵陈蒿汤外洗干预新生儿黄疸,高胆红素血症发生率低,予光疗联合治疗高胆红素血症,黄疸消退快,光疗时间及住院时间短,疗效显著,值得推广。

Objective To explore the clinical effect of external washing with Yinchenhao Tang and early intervention with phototherapy in the treatment of neonatal hyperbilirubinemia.Methods A total of 1643 newborns with jaundice were selected from the Obstetrics Department of Liuzhou Traditional Chinese Medicine Hospital from July 2020 to June 2023.They were fumigated and washed with Yinchenhao Tang(containing 13 kinds of herbs),and 499 cases(30.37%)of neonatal hyperbilirubinemia were diagnosed.They were divided into 3 groups according to the different treatment methods received by the children.168 cases in Group A were treated with phototherapy and traditional Chinese medicine bathing,177 cases in Group B were treated with traditional Chinese medicine bathing,and 154 cases in Group C were treated with phototherapy.By collecting clinical data such as basic maternal and infant information from 3 groups,a database was established to statistically analyze and compare the therapeutic effects of the three groups of cases.Results The jaundice regression time and serum total bilirubin value in group B were higher than those in group A and group C,with statistically significant differences(P<0.05).The time of phototherapy and hospitalization in group A were shorter than those in group C,with statistically significant difference(P<0.05).Conclusion Early external washing with Yinchenhao Tang(containing 13 kinds of herbs)for the intervention of neonatal jaundice has a low incidence of hyperbilirubinemia.The combination of phototherapy and Yinchenhao Tang in the treatment of hyperbilirubinemia has a rapid resolution of jaundice,short phototherapy and hospitalization time,significant therapeutic effect,which is worth promoting.