围绝经期女性输尿管结石术后泌尿系统感染危险因素分析

Analysis on risk factors for urinary tract infection in perimenopausal women undergoing ureteral calculi surgery

目的 探讨围绝经期女性输尿管结石术后泌尿系统感染的危险因素。方法 选择2022年1月—2024年1月金华市中心医院137例围绝经期输尿管结石患者,均行输尿管镜碎石术。记录患者术后泌尿系统感染情况,采用多因素logistic回归模型分析术后泌尿系统感染的危险因素。结果 围绝经期输尿管结石患者137例,术后发生泌尿系统感染25例(18.25%)。单因素分析显示:感染组合并糖尿病比例(28.00%)高于无感染组(9.82%),长期吸烟史比例(48.00%)高于无感染组(12.50%),手术时间>60 min比例(68.00%)高于无感染组(20.54%),术后导尿管留置时间>5 d比例(76.00%)高于无感染组(14.29%),住院时间>10 d比例(32.00%)高于无感染组(8.93%),C-反应蛋白(CRP)水平[(87.42±18.96)mg/L]高于无感染组[(23.15±5.56)mg/L],降钙素原(PCT)水平[(2.61±0.72)μg/L]高于无感染组[(0.95±0.18)μg/L],白细胞(WBC)计数[(13.24±2.87)×10^(9)/L]高于无感染组[(8.85±2.10)×10^(9)/L],差异均有统计学意义(均P<0.05)。多因素logistic回归分析显示:合并糖尿病、长期吸烟史、手术时间、术后导尿管留置时间、住院时间、CRP、PCT、WBC计数为围绝经期女性输尿管结石术后发生泌尿系统感染的独立危险因素。结论 围绝经期女性输尿管结石术后泌尿系统感染受多因素影响,其中合并糖尿病、长期吸烟史、手术时间长、术后导尿管留置时间长、住院时间长、高CRP、高PCT及高WBC计数为危险因素。

Objective To explore the risk factors for urinary tract infection in perimenopausal women undergoing ureteral calculi sur-gery.Methods A total of 137 perimenopausal patients with ureteral calculi in Jinhua Central Hospital from January 2022 to January 2024 were selected,all the patients underwent ureteroscopic lithotripsy.The postoperative urinary system infection status of patients was recorded,the risk factors of postoperative urinary system infection was analyzed using multiple logistic regression analysis.Results Among 137 perim-enopausal patients with ureteral calculi,25 cases(18.25%)were found with urinary tract infection after surgery.Univariate analysis showed that the proportion of diabetes(28.00%)in infection group was higher than that in non-infection group(9.82%),the proportion of long-term smoking history(48.00%)was higher than that in non-infection group(12.50%),the proportion of operation time>60 minutes(68.00%)was higher than that in non-infection group(20.54%),the proportion of indwelling time of urinary catheter after operation>5 days(76.00%)was higher than that in non-infection group(14.29%),the proportion of hospital stay>10 days(32.00%)was higher than that in non-infection group(8.93%),C-reactive protein(CRP)level[(87.42±18.96)mg/L]was higher than that in non-infec-tion group[(23.15±5.56)mg/L],procalcitonin(PCT)level[(2.61±0.72)μg/L]was higher than that in non-infection group[(0.95±0.18)μg/L],white blood cell(WBC)count[(13.24±2.87)×10^(9)/L]was higher than that in non-infection group[(8.85±2.10)×10^(9)/L](all P<0.05).Multivariate logistic regression analysis showed that complicated with diabetes,long-term smok-ing history,operation time,postoperative catheter indwelling time,hospital stay,CRP,PCT,and WBC count were independent risk factors for postoperative urinary system infection in perimenopausal women.Conclusion The occurrence of urinary system infection in perimenopa-usal women with ureteral calculi after operation is affected by many factors,complicated with diabetes,long-term smoking history,long oper-ation time,long indwelling time of urinary catheter after operation,long hospital stay,high CRP,high PCT,and high WBC count are the risk factors.