超声造影下峰值强度、平均渡越时间在子宫内膜癌患者中的检测意义

Detection Significance of Peak Intensity and Mean Transit Time under Ultrasonic Contrast in Patients with Endometrial Cancer

目的:探讨超声造影下峰值强度(PI)、平均渡越时间(MTT)在子宫内膜癌(EC)患者中的检测意义。方法:选取2020年1月—2023年10月江西中医药大学附属医院收治的60例EC患者作为EC组,另选取同期本院收治的子宫内膜良性病变患者60例作为良性病变(BL)组。所有患者均行超声造影,比较EC组和BL组及深肌层浸润组和无或浅肌层浸润组PI、MTT、达峰时间(TTP)、到达时间(AT),并分析上述指标对EC及深肌层浸润的诊断价值。结果:EC组PI高于BL组,MTT短于BL组(t=6.315、3.177,P<0.05);ROC曲线显示,PI、MTT联合诊断EC的AUC为0.861,高于PI的0.799、MTT的0.694(Z=2.015、3.780,P<0.05);深肌层浸润组PI高于无或浅肌层浸润组,MTT短于无或浅肌层浸润组(t=3.901、3.854,P<0.05);ROC曲线显示,PI、MTT联合诊断EC深肌层浸润的AUC为0.902,高于PI的0.792、MTT的0.764(Z=2.345、2.226,P<0.05)。结论:超声造影下PI、MTT对EC及深肌层浸润有一定的诊断价值。

Objective:To explore the detection significance of peak intensity(PI)and mean transit time(MTT)under ultrasonic contrast in patients with endometrial cancer(EC).Method:A total of 60 patients with EC admitted to the Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine from January 2020 to October 2023 were selected as the EC group,and another 60 patients with benign endometrial lesions admitted to our hospital during the same period were selected as the benign lesion(BL)group.All patients underwent ultrasonic contrast,PI,MTT,time to peak(TTP)and arrival time(AT)were compared between EC group and BL group,deep muscle infiltration group and no or shallow muscle infiltration group,and the diagnostic value of the above indexes in EC and deep muscle infiltration were analyzed.Result:PI in EC group was higher than that in BL group,and MTT was shorter than that in BL group(t=6.315,3.177,P<0.05).The ROC curve showed that the AUC of PI and MTT combined diagnosis of EC was 0.861,which was higher than than that of PI(0.799)and MTT(0.694)(Z=2.015,3.780,P<0.05).PI in deep muscle infiltration group was higher than that in no or shallow muscle infiltration group,and MTT was shorter than that in no or shallow muscle infiltration group(t=3.901,3.854,P<0.05).The ROC curve showed that the AUC of PI and MTT combined diagnosis of EC deep muscle infiltration was 0.902,which was higher than that of PI(0.792)and MTT(0.764)(Z=2.345,2.226,P<0.05).Conclusion:PI and MTT under ultrasonic contrast have certain diagnostic value for EC and deep muscle infiltration.