柴胡化学成分及药理作用研究进展

Research progress on chemical composition and pharmacological effects of Bupleuri radix

柴胡为伞形科植物柴胡或狭叶柴胡的干燥根,是目前最常用的传统中药,始载于《神农本草经》。具有抗炎、抗氧化、保肝、抗肿瘤、抗抑郁等多种药理作用,其现代研究中柴胡提取物主要包括柴胡皂苷、黄酮、挥发油等多种化学成分。通过查阅国内外相关文献,本文对柴胡化学成分及药理作用的研究进展进行综述,并指出未来的研究方向,为后续的研究提供一定参考依据。

Bupleuri radix is the dried root of Bupleuri radix or narrow-leaved Bupleuri radix of the umbelliferae family,and it is the most commonly used traditional Chinese medicine,which was first published in Shennong's Classic of Materia Medica.It has a variety of pharmacological effects such as anti-inflammatory,antioxidant,hepatoprotective,antitumor,antidepressant,et al.In the modern study,the extract of Bupleuri radix mainly includes a variety of chemical components such as Bupleuri radix saponin,flavonoids and volatile oil.By reviewing the relevant literature at home and abroad,this paper summarizes the research progress on the chemical composition and pharmacological effects of Bupleuri radix,and points out the future research direction to provide a certain reference basis for the subsequent research.