头孢呋辛钠联合地塞米松治疗未足月胎膜早破产妇的效果

Effect of Cefuroxime Sodium combined with Dexamethasone in the treatment of pregnant women with preterm premature rupture of membranes

目的探讨未足月胎膜早破产妇应用头孢呋辛钠联合地塞米松治疗的作用。方法将仪征市人民医院2019年1月至2024年1月收治的90例未足月胎膜早破产妇纳入研究,采用摸双色球法分为试验组、参照组,各45例。参照组行头孢呋辛钠治疗,试验组加用地塞米松治疗。比较两组的围产期指标、产妇结局、新生儿情况及新生儿结局。结果试验组围产期指标中分娩孕龄大于参照组(P<0.05),产后住院时间、剖宫产率及早产率均少于参照组(P<0.05);试验组产妇不良结局总发生率低于参照组(P<0.05);试验组新生儿1、5、10 min Apgar评分均高于参照组(P<0.05);试验组新生儿不良结局总发生率低于参照组(P<0.05)。结论未足月胎膜早破产妇应用头孢呋辛钠联合地塞米松治疗,能够改善分娩结局及新生儿出生情况,减少新生儿不良结局发生,值得推广。

Objective To explore the role of Cefuroxime Sodium combined with Dexamethasone in the treatment of pregnant women with preterm premature rupture of membranes.Methods A total of 90 pregnant women with preterm premature rupture of membranes admitted to People's Hospital of Yizheng from January 2019 to January 2024 were included in the study.They were divided into the experimental group and reference group by touching bicolor method,with 45 cases in each group.The reference group was treated with Cefuroxime Sodium,and the experimental group was treated with Cefuroxime Sodium combined with Dexamethasone.Perinatal indicators,maternal outcomes,neonatal status,and neonatal outcomes were compared between the two groups.Results The gestational weeks of delivery in the experimental group was greater than that in the reference group(P<0.05).The perinatal hospitalization,cesarean section rate,and premature delivery rate in the experimental group were lower than those in the reference group(P<0.05).The total incidence of adverse maternal outcomes in the experimental group was lower than that in the reference group(P<0.05).The Apgar scores of the newborns at 1,5,and 10 min postpartum in the experimental group were higher than those in the reference group(P<0.05).The total incidence of adverse neonatal outcomes in the experimental group was lower than that in the reference group(P<0.05).Conclusion The combination of Cefuroxime Sodium and Dexamethasone in pregnant women with preterm premature rupture of membranes can improve delivery outcomes and neonatal births,and reduce the occurrence of adverse neonatal outcomes,which is worth promoting.