自身免疫相关性癫间的诊治进展

Progress in Diagnosis and Treatment of Autoimmune-associated Epilepsies

近年来,免疫因素在癫间发作中的作用越来越得到普遍认同。自身免疫相关性癫间是尽管进行了充分的免疫治疗,但癫间发作仍持续存在的一种慢性疾病,为患者带来了重大的经济和心理负担。自身免疫相关性癫间的病理生理机制尚不明确,缺乏有效的预防和治疗方法。文中将对自身免疫相关性癫间的现有临床特点、病理生理机制、诊断、治疗进行阐述,以期为自身免疫相关性癫间的早期诊断和治疗提供新思路。

In recent years,the role of immune factors in epileptic seizures has been increasingly widely recognized.Autoimmune-associated epilepsy is a chronic condition in which seizures persist despite adequate immunotherapy,presenting a significant economic and psychological burden on patients.The pathophysiological mechanism of autoimmune-associated epilepsies is not clear,and there is a lack of effective prevention and treatment.The clinical features,pathophysiological mechanisms,diagnosis and treatment of autoimmune-associated epilepsies were elaborated to provide new ideas for the early diagnosis and treatment of autoimmune-associated epilepsies.