2005-2022年山东省急性出血性结膜炎流行特征和空间分布分析

Epidemiological characteristics and spatial distribution of AHC in Shandong province,2005-2022

目的 分析山东省急性出血性结膜炎(acute hemorrhagic conjunctivitis,AHC)的流行特点和时空分布特征,探讨其流行趋势和重点发病地区,为完善防控措施提供参考依据.方法 通过中国传染病报告信息管理系统获取2005-2022年山东省AHC监测资料,并对报告病例进行描述性分析与空间自相关分析.结果 2005-2022年山东省AHC年均发病率为0.73/10万,无死亡病例,于2007年、2010年、2018年和2022年出现发病高峰.山东省AHC发病可分为三个阶段,2005-2009年、2010-2017年和2018-2022年,平均发病率分别为0.20/10万、0.81/10万和1.12/10万.年均发病率居前两位的地区为德州市(5.16/10万)、聊城市(3.26/10万);各年龄段均有AHC病例发生,60~69岁(0.89/10万)和20~29岁(0.86/10万)年龄组高发;男女性别比1.23∶1,性别比近年来呈下降趋势.2005-2022年山东省AHC发病率在整体上呈现空间聚集性分布(P<0.05);局部自相关"高-高"聚集区主要分布在德州市的西北部,聊城市的北部及青岛市崂山区、市北区.结论 2005-2022年山东省AHC发病较低,但近年呈波动上升趋势,60~69岁、20~29岁年龄段高发,空间上整体呈聚集性分布,德州市和聊城市为病例高聚集区.

Objective To analyze the epidemic characteristics and spatial distribution of acute hemorrhagic conjunctivitis(AHC)in Shandong province and explore the epidemic trend and key incidence areas,so as to provide reference for improving prevention and control measures.Methods Surveillance data of AHC in Shandong province from 2005 to 2022 were obtained through China Infectious Disease Reporting Information Management System.The descriptive analysis and spatial auto-correlation analysis were performed for reported cases.Results From 2005 to 2022,the average annual incidence of AHC in Shandong province was 0.73/100000,with no death cases.The incidence peaks were observed in 2007,2010 and 2018,respectively.The incidence of AHC in Shandong province can be divided into three stages,from 2005 to 2009,2010 to 2017 and 2018 to 2022,and the average incidence was 0.20/100,000,0.81/100,000 and 1.12/100000,respectively.The average incidence rate of Dezhou city(5.16/100000)and Liaocheng city(3.26/100000)ranked first and second.AHC cases occurred in all age groups,with higher incidence in age groups of 60-69 and 20-29 years old.The male to female ratio was 1.23∶1 which showed a trend of decreasing in recent years.The incidence of AHC in Shandong Province from 2005 to 2022 presented a spatial aggregation distribution in general(P<0.05).Local auto-correlation"high-high"agglomeration areas were mainly distributed in the northwest of Dezhou city,the north of Liaocheng city as well as Laoshan district and Shibei district of Qingdao city.Conclusions From 2005 to 2022,the incidence of AHC was relatively low in Shandong province,but it showed a fluctuating upward trend in recent years.The incidence was higher in the age groups of 60-69 years and 20-29 years old.The spatial distribution of AHC was generally clustered,Dezhou city and Liaocheng city were the areas with high concentration of cases.