左侧上颌骨牙源性影细胞癌1例报告及文献复习

Ghost cell odontogenic carcinoma in the left maxilla:a case report and literature review

牙源性影细胞癌(ghost cell odontogenic carcinoma,GCOC)是起源于颌骨的罕见恶性肿瘤,其在临床与影像上可表现出与良性牙源性肿瘤不同的恶性特征,例如肿瘤体积大、伴有周围骨质破坏等,但不具备特异性,因此往往依靠病理形态学确诊。GCOC的特征在于异常角质化的影细胞、小的基底样细胞和类牙本质沉积。准确诊断该病有重要的临床意义并有利于患者预后。本文报告1例左侧上颌骨GCOC,并结合相关文献进行复习。

Ghost cell odontogenic carcinoma(GCOC)is a rare malignant tumor originating in the jawbone,which can exhibit clinically and radiographically malignant features distinct from benign odontogenic tumors,such as large tumor size and adjacent bone destruction,but these features lack specificity;therefore,diagnosis often relies on pathological morphology.Characterized by abnormal keratinized ghost cells,small basaloid cells,and dentin-like deposits,accurate identification of GCOC holds significant clinical importance and is beneficial for patient prognosis.This paper reported a case of GCOC in the left maxilla and reviewed the relevant literature.