惠水地区泌尿系结石患者结石成分分析和代谢评估

Component analysis and metabolic evaluation of patients with urinary calculi in Huishui area

目的分析惠水地区泌尿系结石患者结石成分和代谢评估。方法分析2023年1月至2024年7月惠水地区226例泌尿系结石患者结石成分及24 h尿液分析结果。226例患者中,男148例,女78例,年龄(48.7±6.9)岁。采用χ^(2)检验进行统计分析。结果216例结石成分分析中,草酸钙结石74例(34.26%),尿酸结石17例(7.87%),磷酸钙结石4例(1.85%),各类混合性结石121例(56.02%)。226例24 h尿液分析检测中,220例(97.35%)存在代谢异常;其中,高钙尿20例(8.85%),低镁尿179例(79.20%),高钠尿35例(15.49%),高尿酸尿12例(5.31%),高磷尿1例(0.44%),低尿量76例(33.63%);单纯1种代谢异常94例(41.59%),合并2种71例(31.42%),合并3种7例(3.10%),合并4种3例(1.33%)。结论惠水地区泌尿系结石发病率与区域环境、水质以及代谢异常相关。

Objective To analyze the components of calculi and metabolic evaluation of patients with urinary calculi in Huishui area.Methods From January 2023 to July 2024,the components of calculi and 24-hour urine analysis results of 226 patients with urinary calculi in Huishui area were analyzed.Among the 226 patients,there were 148 males and 78 females;they were(48.7±6.9)years old.The χ^(2) test was used for the statistical analysis.Results Among the 216 cases who took component analysis,74 cases(34.26%)were identified as calcium oxalate calculi,17 cases(7.87%)uric acid calculi,and 4 cases(1.85%)calcium phosphate calculi;a total of 121 cases(56.02%)presented various types of mixed calculi.Among the 226 cases who took 24-hour urine analysis,220 cases(97.35%)had abnormal metabolism;there were 20 cases(8.85%)of hypercalciuria,179 cases(79.20%)of hypomagnesuria,35 cases(15.49%)of hypernatriuria,12 cases(5.31%)of hyperuricosuria,1 case(0.44%)of hyperphosphaturia,and 76 cases of low urine volume;94 cases(41.59%)had 1 abnormal metabolism,71 cases(31.42%)2,7 cases(3.10%)3,and 3 cases(1.33%)4.Conclusion The prevalence of urinary calculi in Huishui area is associated with the local environment,water quality,and metabolic disorders.