对比乳腺癌保乳手术和非保乳手术对术后远期复发率的影响

Comparison of Long-Term Recurrence Rate after Breast Conserving Sur⁃gery and Non Breast Conserving Surgery for Breast Cancer

目的分析保乳、非保乳手术对乳腺癌患者远期复发率的影响。方法非随机选取2019年11月—2021年11月江阴市人民医院78例乳腺癌患者为研究对象,根据治疗方案不同分为保乳组、根治组,各39例。保乳组行保乳手术,根治组行非保乳手术,对比两组围术期指标、并发症、远期复发率。结果保乳组手术时间短于根治组,出血量、引流量低于根治组,切口长度、出院时间短于根治组,差异有统计学意义(P均<0.05)。保乳组并发症发生率为2.56%(1/39),低于根治组的15.38%(6/39),差异有统计学意义(χ^(2)=3.924,P<0.05)。两组半年、1年、2年的复发率对比,差异无统计学意义(P均>0.05)。结论保乳手术一般情况下不会增加乳腺癌复发率,且能缩小切口长度,提升乳房美观度,减少并发症,相比非保乳手术优势更多,因此更推荐患者行保乳手术。

Objective To analyze the effect of breast conserving and non breast conserving surgery on the long-term recurrence rate of breast cancer patients.Methods A total of seventy-eight patients with breast cancer in Jiangyin People′s Hospital from November 2019 to November 2021 were non-randomly selected as the research objects.According to different treatment plans,they were divided into breast-conserving group and radical treatment group,thirty-nine cases in each group.Breast-conserving group received breast-conserving operation,radical group received non-breast-conserving operation.Perioperative indexes,complications and long-term recurrence rates were compared between the two groups.Results The operation time of breast-conserving group was shorter than that of radical group,the blood loss and drainage volume were lower than that of radical group,the incision length and discharge time were shorter than that of radical group,and the differences were statistically significant(all P<0.05).The incidence of complications in the nursing group was 2.56%(1/39),lower than 15.38%(6/39)in the radical treatment group,and the difference was statistically significant(χ2=3.924,P<0.05).There were no statistically significant differences in the recurrence rate of half a year,1 year and 2 years between the two groups(all P>0.05).Conclusion Breast conserving surgery generally does not increase the recurrence rate of breast cancer,and can reduce the incision length,improve the beauty of the breast,and reduce complications.Compared with non breast conserving surgery,breast conserving surgery has more advantages.Therefore,breast conserving surgery is more recommended for patients.