清创术联合负压封闭引流术应用于糖尿病足患者创面治疗的临床观察

Clinical Observation of Debridement Combined with Vacuum Sealing Drainage in the Treatment of Patients with Diabetic Foot Wound

目的:分析清创术联合负压封闭引流术应用于糖尿病足患者创面治疗的临床效果。方法:选取2019年1月—2023年11月天津二七二医院收治的78例糖尿病足患者为研究对象,根据电脑随机法将其分为研究组与对照组,各39例。对照组采用清创术治疗,研究组在对照组基础上加用负压封闭引流术治疗,对比分析两组治疗总有效率、疼痛感、炎症因子及创面愈合时间。结果:对照组治疗总有效率为82.05%,低于研究组的97.44%,差异有统计学意义(P<0.05)。治疗后,研究组疼痛评分低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组白细胞计数、中性粒细胞百分比、淋巴细胞计数均低于对照组,差异均有统计学意义(P<0.05)。研究组创面愈合时间短于对照组,差异有统计学意义(P<0.05)。结论:糖尿病足患者创面治疗时采用清创术联合负压封闭引流术,有助于提升治疗效果,也有助于减轻疼痛感,改善炎症状态,并缩短创面愈合时间。

Objective:To analyze the effect of debridement combined with vacuum sealing drainage in the treatment of patients with diabetic foot wound.Methods:A total of 78 patients with diabetic foot admitted to Tianjin 2702 Hospital from January 2019 to November 2023 were selected as the study objects,and were divided into a study group and a control group according to computer randomized method,with 39 cases in each group.The control group was treated with debridement,and the research group was treated with vacuum sealing drainage on the basis of the control group.The total effective rate,pain sensation,inflammatory factors and wound healing time of the two groups were compared and analyzed.Results:The effective rate of the control group was 82.05%,which was lower than 97.44%of the study group,the difference was statistically significant(P<0.05).After treatment,the pain scores of the study group was lower than that of the control group,the difference was statistically significant(P<0.05).After treatment,the white blood cell count,neutrophil percentage and lymphocyte count in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).The wound healing time of the study group was shorter than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Debridement combined with vacuum sealing drainage in the treatment of patients with diabetic foot is helpful to improve the therapeutic effect,relieve pain and improve inflammation,and shorten the wound healing time.