熟地丹杞黄精胶囊抗疲劳功效研究

Study on Anti-Fatigue Effect of Shudi Danqi Huangjing Capsule

目的:研究熟地丹杞黄精胶囊的抗疲劳作用。方法:选用SPF小鼠,随机分4组,1组为对照组,饲以蒸馏水,其余3组分别灌胃0.75、1.50、2.25 g/kg BW的胶囊内容物,30 d后测定小鼠游泳时间、血乳酸及血清尿素氮、肝糖原的水平。结果:与阴性对照组比较,2.25 g/kg BW组小鼠延长了负重游泳时间,减少了游泳后、休息后血乳酸值,以及游泳后的血乳酸曲线下面积;0.75 g/kg BW组小鼠可有效降低血清尿素氮值。结论:熟地丹杞黄精胶囊具有显著抗疲劳作用。

Objective:To study the anti-fatigue effect of Shudi Danqi Huangjing capsule.Methods:SPF mice were randomly divided into 4 groups.The mice in the control group were fed with distilled water,while the mice in the other 3 groups were fed with capsule contents in 0.75,1.50,and 2.25 g/kg BW.The effect was evaluated by the time of swimming,the level of lactic acid and serum urea nitrogen in the blood,and the level of glycogen in the liver,after 30 days.Results:Compared with the negative control group,mice treated with 2.25 g/kg BW had significantly longer time of heavy load swimming,the blood lactic acid value after swimming and rest and the area under the blood lactic acid curve after swimming were reduced.The mice treated with 0.75g/kg BW can effectively reduce serum urea nitrogen.Conclusion:Shudi Danqi Huangjing capsule has the effect of anti-fatigue.