基于脑肠轴学说探讨以脾肾论治血管性痴呆

Exploration of Treating Vascular Dementia Based on Spleen-Kidney Theory According to the Brain-Intestinal Axis Hypothesis

随着人口老龄化的提高,血管性痴呆是仅次于阿尔茨海默病之后导致痴呆的第二大类型。我国血管性痴呆患者数量逐年增加,已然成为一个社会关注的热点话题。结合现代医学对脑肠轴学说的研究,发现痴呆的病机总属髓减脑消,根源于脾肾亏虚,病因多为髓海不足、邪侵脑肠、先后天失养、经脉不濡等,故在治疗痴呆的过程中,不仅要充髓益窍,更要顾护脾胃,以后天滋养先天,采用“健脾益肾化浊方”为底方,随证化裁,以取得确切疗效。

With the increase of population aging,vascular dementia is the second most common type of dementia caused after Alzheimer's disease.The number of patients with vascular dementia is increasing year by year in China,and it has become a hot topic of social concern.Combined with modern medical research on the brain-intestinal axis doctrine,it is believed that the pathogenesis of dementia is always a result of the reduction of the medulla oblongata and the elimination of the brain,which is rooted in the deficiencies of the spleen and kidney,and that the causes of the disease are the insufficiency of the medulla oblongata,the evil encroachment on the brain and intestines,the loss of nourishment of the successive heavens,and the lack of moistening of the meridians and veins.The formula of“strengthening the spleen,benefiting the kidneys and removing turbidity”was used as the base formula,which was tailored according to the evidence,and the therapeutic effect was exact.