2023年上海市浦东新区犬钩端螺旋体感染和风险因素横断面调查

Cross-sectional Investigation on Canine Leptospira Infection and Risk Factors in Pudong New Area of Shanghai City in 2023

为了解上海市浦东新区犬钩端螺旋体感染情况,并分析影响感染的风险因素,使用犬钩端螺旋体抗体ELISA检测试剂盒,对2023年随机抽取的犬血清样品进行检测,并通过单因素分析和多变量Logistic回归分析,建立犬感染钩端螺旋体的风险模型。结果显示:2023年浦东新区犬钩端螺旋体总感染率达9.46%(95%CI:6.37%-10.07%);单因素分析结果显示,犬只未免疫钩端螺旋体疫苗、犬主不了解该病、犬只年龄>1岁以及未饲喂商品狗粮等因素与犬感染钩端螺旋体有关联;回归分析结果显示,犬只未免疫是感染钩端螺旋体的风险因素(P<0.05)。经Hosmer-Lemeshow拟合优度检验,该回归模型的卡方值χ^(2)=2.550,P>0.05,ROC曲线下面积为0.79,说明该模型具有较好的预测价值。本调查为浦东新区犬钩端螺旋体病免疫、监测和防控提供了基础数据。

In order to investigate the status of canine Leptospira infection in Pudong New Area of Shanghai City in 2023,and to analyze the responsible risk factors,canine serum samples randomly collected in 2023 were detected by ELISA kits,and a risk model of canine infection with Leptospira was established through univariate analysis and multivariate Logistic regression analysis.The results showed that the total infection rate of canine Leptospira reached 9.46%(95%CI:6.37%-10.07%);the univariate analysis revealed that the infection was associated with dogs without vaccination against Leptospira,poor awareness of dog owners about the disease,dogs aged above one year old,feeding without commercial dog food and other factors;and the regression analysis revealed that dogs without vaccination was a risk factor for Leptospira infection(P<0.05).Hosmer-Lemeshow goodness-of-fit test showed that the Chi-square value of the regression model was 2.550,P>0.05,and the area under ROC curve was 0.79,indicating a good predictive value.The general data was provided by the investigation for vaccination,monitoring,prevention and control towards canine leptospirosis in Pudong New Area.