合子草化学成分及生物活性的研究进展

Research Progress on the Chemical Constituents and Biological Activities of Actinostemma lobatum Griff.

合子草含有皂苷类、多酚类、微量脂质伴随物等多种植物化合物,且研究表明合子草具有抗肿瘤、抑菌、抗炎、抗凝血等多种生物活性,具有较高的开发应用价值。然而,合子草资源尚未得到有效利用,造成资源的严重浪费;学界尚未深入研究合子草中有效化学成分、生物活性及其潜在的分子作用机制。因此,从合子草的化学成分、生物活性等方面综述了合子草研究的现状,并指出了在食品和医药等领域的应用前景,为合子草资源的开发与利用提供一定的依据。

Actinostemma lobatum Griff.contains saponins,polyphenols,lipids,and other compounds.It has been proved that A.lobatum possesses several biological activities,such as anti-tumor,antibacterial,anti-inflammatory,antithrombotic.These activities make it high value of development and application.Up to now,A.lobatum resource has not been effectively developed,resulting in a serious waste.The effective chemical constituents,biological activities,and the underlying mechanism of A.lobatum.have not been studied in-depth.Therefore,this article reviewed the research progress of chemical composition,biological activity,and toxicology of A.lobatum.Meanwhile,the review also pointed out A.lobatum.application pro-spects for food and pharmaceutical industries,which would lay a certain foundation for its development and application.