宫腔镜下子宫内膜微创术对女性不孕症患者术后子宫内膜容受性的影响

Effect of Minimally Invasive Endometrial Therapy under Hysteroscopy on Uterine Endometrial Receptivity in Women with Infertility

【目的】探讨宫腔镜下子宫内膜微创术对女性不孕症患者术后子宫内膜容受性的影响。【方法】选取2021年1月至2022年12月在本院诊治的50例女性不孕症患者,按照随机数字表法分为对照组(给予常规药物治疗)和观察组(在对照组基础上行宫腔镜下子宫内膜微创术治疗),每组25例。比较两组患者治疗前后子宫内膜血流参数及子宫内膜容受性。【结果】治疗前,两组患者子宫动脉血流的搏动指数(PI)和阻力指数(RI)以及子宫内膜厚度比较,差异无统计学意义(P>0.05);与治疗前比较,两组患者治疗后1周子宫动脉血流的PI和RI以及子宫内膜厚度均有改善(P<0.05),且观察组子宫动脉血流的PI和RI以及子宫内膜厚度改善更明显,差异均有统计学意义(P<0.05)。【结论】对女性不孕症患者采用宫腔镜下子宫内膜微创术,可改善患者子宫内膜血流参数及子宫内膜容受性,从而达到提高胚胎着床率和妊娠率的目的。

【Objective】To investigate the effect of hysteroscopic endometrial minimally invasive surgery on postoperative endometrial receptivity in female infertility patients.【Methods】A total of 50 female infertility patients diagnosed and treated in our hospital from January 2021 to December 2022 were selected and divided into the control group(receiving conventional drug treatment)and the observation group(receiving hysteroscopic endometrial minimally invasive surgery on the basis of control group)according to random number table,with 25 cases in each group.The endometrial blood flow parameters and endometrial receptivity were compared between the two groups before and after treatment.【Results】Before treatment,there were no significant differences in uterine artery blood flow pulsatility index(PI)and resistance index(RI)as well as endometrial thickness between the two groups(P>0.05).One week after treatment,the PI and RI of uterine artery blood flow and endometrial thickness of the two groups were improved in both groups(P<0.05).In addition,the PI and RI of uterine artery blood flow and endometrial thickness in the observation group improved more significantly,and the differences were statistically significant(P<0.05).【Conclusion】Hysteroscopic endometrial minimally invasive surgery for female infertility patients can improve endometrial blood flow parameters and endometrial acceptability to improve the implantation rate and pregnancy rate.