复方聚乙二醇联合柴芍承气汤在无痛结肠镜检查肠道准备中的应用效果

目的探讨复方聚乙二醇电解质散联合柴芍承气汤在无痛结肠镜检查前肠道准备中的效果,旨在提高患者的依从性及肠道准备质量。方法将519例拟行无痛结肠镜检查的患者随机分为观察组和对照组,观察组在检查前一天20时口服复方聚乙二醇电解质散68.56 g(1000 mL)和柴芍承气汤1剂(160 mL);检查当天4时,再次口服复方聚乙二醇电解质散;对照组在检查前一天20时口服复方聚乙二醇电解质散137.12 g(2000 mL),检查当天4时,再次口服复方聚乙二醇电解质散68.56 g(1000 mL)。完成肠道准备6 h后进行无痛结肠镜检查。比较两组在肠道准备清洁度评分、充分肠道准备率、结肠息肉检出率、结肠息肉检出数目、患者不良反应以及再次肠道准备接受度等方面的差异。结果观察组患者肠道准备波士顿评分总分和充分肠道准备率明显高于对照组,且观察组各段肠道评分均高于对照组,差异有统计学意义(P<0.05)。观察组息肉检出率33.5%高于对照组的29.4%,但差异无统计学意义(P>0.05)。观察组≤5 mm息肉数高于对照组,差异有统计学意义(P<0.05)。观察组出现腹痛腹胀的比例显著低于对照组(P<0.05);两组患者再次肠道准备接受度比较,差异无统计学意义(P>0.05)。结论联合应用复方聚乙二醇电解质散和柴芍承气汤进行肠道准备,能显著改善患者肠道准备效果。

Objective To explore the effect of combined polyethylene glycol electrolyte powder and Chaishaochengqi decoction in bowel preparation before painless colonoscopy,aiming to improve patient compliance and bowel preparation quality.Methods A total of 519 patients scheduled for painless colonoscopy were randomly divided into the observation group and the control group.The observation group took polyethylene glycol electrolyte powder 68.56 g(1000 mL)and Chaishaochengqi decoction 1 dose(160 mL)orally at 20:00 the day before the examination;and polyethylene glycol electrolyte powder 68.56 g(1000 mL)again at 4:00 on the day of the examination.The control group took polyethylene glycol electrolyte powder 137.12 g(2000 mL)orally at 20:00 the day before the examination,and polyethylene glycol electrolyte powder 68.56 g(1000 mL)again at 4:00 on the day of the examination.Painless colonoscopy was performed 6 hours after completing bowel preparation.The differences in bowel preparation cleanliness score,adequate bowel preparation rate,colon polyp detection rate,number of colon polyps detected,patient adverse reactions,and acceptance of repeat bowel preparation between the two groups were compared.Results The total Boston score and the rate of adequate bowel preparation in the observation group were significantly higher than those in the control group,and the bowel scores of each segment in the observation group were all higher than those in the control group,with statistically significant differences(P<0.05).The polyp detection rate in the observation group was 33.5%,higher than the control group's 29.4%,but the difference was not statistically significant(P>0.05).The number of polyps≤5 mm in the observation group was higher than that in the control group,with statistically significant differences(P<0.05).The proportion of patients with abdominal pain and bloating in the observation group was significantly lower than that in the control group(P<0.05),there was no statistically significant difference in the acceptance of repeat bowel preparation between the two groups(P>0.05).Conclusion The combined use of polyethylene glycol electrolyte powder and Chaishaochengqi decoction for bowel preparation can significantly improve the effect of bowel preparation.