加味四逆散联合针刺治疗膀胱过度活动综合征的临床疗效观察

Clinical Efficacy Observation of Modified Sini Powder Combined with Acupuncture in the Treatment of Overactive Bladder Syndrome

目的探讨加味四逆散联合针刺治疗膀胱过度活动综合征的临床疗效。方法选择2022年11月—2023年12月南京中医药大学附属苏州市中医医院收治的72例膀胱过度活动综合征患者为研究对象,按随机数字表法将其分为对照组(n=33)和治疗组(n=39)。对照组采用酒石酸托特罗定治疗,治疗组采用加味四逆散联合针刺治疗。比较两组的临床症状、症状评分、生活质量、临床疗效、不良反应发生情况。结果治疗后,治疗组白天排尿次数、夜间排尿次数、尿急次数、尿失禁次数均少于对照组,组间差异有统计学意义(P<0.05);治疗组膀胱过度活动综合征症状评分量表、King健康问卷评分均低于对照组,组间差异有统计学意义(P<0.05);治疗组治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗组不良反应发生率为5.12%,低于对照组的27.27%,差异有统计学意义(P<0.05)。结论加味四逆散联合针刺治疗膀胱过度活动综合征安全有效,具有一定的临床价值。

Objective Exploring the clinical efficacy of modified Sini powder combined with acupuncture in the treatment of overactive bladder syndrome.Methods A total of 72 patients with overactive bladder syndrome admitted to Nanjing University of Traditional Chinese Medicine Affiliated Suzhou Traditional Chinese Medicine Hospital from November 2022 to December 2023 were selected as the research subjects,according to the random number table method,they were divided into a control group(n=33)and a treatment group(n=39).The control group was treated with tolterodine tartrate,while the treatment group was treated with modified Sini powder combined with acupuncture.Compare the clinical symptoms,symptom scores,quality of life,clinical efficacy,and occurrence of adverse reactions between two groups.Results After treatment,the frequency of daytime urination,nighttime urination,urgency,and incontinence in the treatment group were all lower than those in the control group,the differences between the groups were statistically significant(P<0.05);the Symptom Scoring Scale for Overactive Bladder Syndrome and the King Health Questionnaire scores in the treatment group were lower than those in the control group,the differences between the groups were statistically significant(P<0.05);the total effective rate of the treatment group was higher than that of the control group,the difference was statistically significant(P<0.05);the incidence of adverse reactions in the treatment group was 5.12%,which was lower than 27.27% in the control group,the difference was statistically significant(P<0.05).Conclusion Modified Sini powder combined with acupuncture is safe and effective in treating overactive bladder syndrome,and has certain clinical value.