中药穴位敷贴在乳腺癌化疗所致恶心呕吐患者中的应用效果观察

Observation on the Effect of Acupoint Application of Traditional Chinese Medicine in Patients with Nausea and Vomiting Caused by Breast Cancer Chemotherapy

目的探讨中药穴位敷贴在乳腺癌化疗所致恶心呕吐患者中的应用效果。方法选取2022年4月—2023年4月上海中医药大学附属龙华医院收治的80例乳腺癌化疗患者为研究对象,采取随机数字表法将其分成对照组和干预组,每组40例。对照组开展常规护理,干预组在对照组基础上给予中医穴位敷贴干预。比较两组患者的恶心呕吐发生情况、心理状态、生活质量和足程化疗完成情况。结果干预第14天、第21天,干预组化疗相关性恶心呕吐发生程度均低于对照组,组间差异有统计学意义(P<0.05)。干预21 d后,干预组的焦虑自评量表评分(43.47±4.22)分低于对照组的(53.75±4.55)分,生活功能量表评分(105.28±5.32)分高于对照组的(90.52±4.50)分,组间差异有统计学意义(P<0.05)。干预组足程化疗完成率为85.00%,高于对照组的62.50%,差异有统计学意义(P<0.05)。结论中药穴位敷贴在乳腺癌化疗所致恶心呕吐患者中的应用效果显著,能够有效降低患者化疗相关性恶心呕吐的发生率,改善患者心理状态,提高患者生活质量,促进足程化疗的完成,值得推广。

Objective To investigate the effect of acupoint application of traditional Chinese medicine in patients with nausea and vomiting caused by breast cancer chemotherapy.Methods Eighty patients with breast cancer undergoing chemotherapy in Longhua Hospital,Shanghai University of Traditional Chinese Medicine from April 2022 to April 2023 were selected as the research objects,and they were divided into a control group and an intervention group according to random number table method,with 40 cases in each group.The control group was given routine nursing,and the intervention group was given acupoint application of traditional Chinese medicine intervention on the basis of the control group.The incidence of nausea and vomiting,psychological state,quality of life and completion of fall course chemotherapy were compared between the two groups.Results On the 14th and 21st day of intervention,the incidence of chemotherapy related nausea and vomiting in the intervention group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).After 21 days of intervention,the Self Rating Anxiety Scale score of the intervention group was(43.47±4.22)points,which was lower than(53.75±4.55)points of the control group,and the Life Function Scale score was(105.28±5.32)points,which was higher than(90.52±4.50)points of the control group,and the differences between the groups were statistically significant(P<0.05).The completion rate of full course chemotherapy in the intervention group was 85.00%,which was higher than 62.50% in the control group,and the difference was statistically significant(P<0.05).Conclusion The effect of acupoint application of treaditional Chinese medicine in breast cancer patients with nausea and vomiting caused by chemotherapy is significant,which can effectively reduce the incidence of patients with chemotherapy-related nausea and vomiting,improve the psychological state of patients,improve the quality of life of patients,and promote the completion of fall course chemotherapy,which is worthy of promotion.