胃镜联合超声小探头在胃癌前病变诊断中的应用价值

The Application Value of Gastroscopy Combined with Ultrasound Small Probe in the Diagnosis of Gastric Precancerous Lesions

目的:研究胃镜联合超声小探头在胃癌前病变诊断中的应用效果。方法:从2022年3月~2023年12月在本院进行诊治的疑似胃癌前病变患者中筛选76例纳入研究的范围,所有患者均行胃镜、超声小探头检查,以病理诊断结果作为金标准,计算、比较胃镜、超声小探头单一和联合检查在胃癌前病变中的诊断效能,对比不同的胃癌前病变病灶、级别的检出情况。结果:胃镜联合超声小探头检查诊断胃癌前病变的准确率、特异度、敏感度、阳性预测率、阴性预测率、不同癌前病变病灶个数高于胃镜检查,差异有统计学意义(P<0.05)。胃镜联合超声小探头检查对低级别上皮内瘤变检出率高于胃镜检查,差异有统计学意义(P<0.05);胃镜检查与胃镜联合超声小探头检查对高级别上皮内瘤变的检出率比较,差异无统计学意义(P>0.05)。结论:胃镜联合超声小探头在胃癌前病变诊断中效果确切,诊断的准确率、特异度、敏感度等均比较高,同时还能更加准确地对病灶的性质进行判断,为制订治疗措施提供重要的临床依据,临床价值高。

Objective:To study the application effect of gastroscopy combined with ultrasound small probe in the diagnosis of gastric precancerous lesions.Methods:From March 2022 to December 2023,76 suspected patients with gastric precancerous lesions who underwent diagnosis and treatment in our hospital were selected and included in the study.All patients underwent gastroscopy and ultrasound small probe examination,and the pathological diagnosis results were used as the gold standard.The diagnostic efficacy of gastroscopy and ultrasound small probe single and combined examinations in gastric precancerous lesions,as well as the detection of different levels of gastric precancerous lesions and lesions,were calculated and compared.Results:The accuracy,specificity,sensitivity,positive predictive rate,negative predictive rate,and number of different precancerous lesions in the diagnosis of gastric cancer by gastroscopy combined with ultrasound small probe examination were higher than those by gastroscopy examination,and the difference was statistically significant(P<0.05).The detection rate of low-grade intraepithelial neoplasia using gastroscopy combined with ultrasound small probe examination is higher than that using gastroscopy examination,and the difference is statistically significant(P<0.05);There was no statistically significant difference in the detection rate of high-grade intraepithelial neoplasia between gastroscopy and gastroscopy combined with ultrasound small probe examination(P>0.05).Conclusion:The combination of gastroscopy and ultrasound small probe is effective in the diagnosis of precancerous lesions of gastric cancer,with high accuracy,specificity,sensitivity,and more accurate judgment of the nature of the lesion.It provides important clinical basis for formulating treatment measures,has high clinical value.