诺唯赞量子点荧光分析仪对检验小儿感染性肺炎的应用价值

The Application Value of Vazyme Quantum Dot Fluorescence Analyzer to Test Pediatric Infectious Pneumonia

目的:分析诺唯赞量子点荧光分析仪对检验小儿感染性肺炎的应用价值。方法:纳入2023年4月1日~2023年8月31日医院临床收治的小儿感染性肺炎患者93例为研究对象,采用诺唯赞全自动量子点荧光免疫分析仪QD-S1200、迈瑞BC-6000plus全自动血液细胞分析仪以及普门特定蛋白分析仪PA-900检测93例患儿白细胞、超敏-C反应蛋白(hs-CRP)、白细胞介素-6 (IL-6)、降钙素原(PCT)、血清淀粉样蛋白A(SAA),探究不同检测仪器在小儿感染性肺炎诊断中的应用价值。结果:利用诺唯赞全自动量子点荧光免疫分析仪QDS1200、迈瑞BC-6000plus全自动血液细胞分析仪以及普门特定蛋白分析仪PA-900检测检出93例患儿白细胞(10.12±0.23)×10~9/L、hs-CRP (21.01±7.85) mg/L、PCT (0.44±0.06) ng/mL、IL-6 (39.24±6.32) pg/mL、SAA(101.28±29.63) mg/L;诺唯赞全自动量子点荧光免疫分析仪QD-S1200阳性检出率为100.00%,迈瑞BC-6000plus全自动血液细胞分析仪阳性检出率为97.85%,普门特定蛋白分析仪PA-900阳性检出率为96.77%,三组间差异无统计学意义(P>0.05);采用诺唯赞全自动量子点荧光免疫分析仪QD-S1200在感染性肺炎患儿不同指标检验中检出时间更短,差异有统计学意义(P<0.05);诺唯赞全自动量子点荧光免疫分析仪QD-S1200对hs-CRP、PCT、IL-6、SAA2个不同浓度质控品测定中,批内精密度<10%,批间精密度<15%,5项指标检测精密度较高。结论:诺唯赞全自动量子点荧光免疫分析仪QD-S1200检测小儿感染性肺炎相关实验室指标水平阳性率高,且检测等待时间更短,临床检测综合应用价值高。

Objective:To analyze the application value of the Vazyme quantum dot fluorescence analyzer in detecting infectious pneumonia in children.Methods:A study included 93 pediatric infectious pneumonia patients from April 1,2023 to August 31,2023,white blood cells of QD-S1200,Mindray BC-6000plus and PA-900(white blood cell,WBC),hypersensitivity-C-reactive protein(hypersensitivity-C-reactive protein;hs-CRP),interleukin-6(interleukin-6,IL-6),procalcitonin(PCT),and serum amyloid A(serum amyloid protein A,SAA),explore the application value of different monitoring instruments in the diagnosis of pediatric infectious pneumonia.Results:93 pediatric patients were detected to have white blood cells(10.12±0.23)×109/L,hs CRP(21.01±7.85)mg/L,PCT(0.44±0.06)ng/mL,IL-6(39.24±6.32)pg/mL,and SAA(101.28±29.63)mg/L using the Vazyme fully automated quantum dot fluorescence immunoassay analyzer QDS120,Mindray BC-6000plus fully automated hematology analyzer,and Pumen specific protein analyzer PA-900;The positive detection rate of the Vazyme fully automatic quantum dot fluorescence immunoassay analyzer QD-S1200 was 100.00%,the positive detection rate of the Mindray BC-6000plus fully automatic blood cell analyzer was 97.85%,and the positive detection rate of the Pumen specific protein analyzer PA-900 was 96.77%.There was no statistically significant difference among the three groups(P>0.05);The detection time of different indicators in children with infectious pneumonia was shorter and the difference was statistically significant(P<0.05)using the Vazyme fully automatic quantum dot fluorescence immunoassay analyzer QD-S1200;In the determination of two different concentration quality control samples,hs CRP,PCT,IL-6,and SAA,using the Vazyme fully automatic quantum dot fluorescence immunoassay analyzer QD-S1200,the intra batch precision was less than 10%,the inter batch precision was less than 15%,and the detection precision of five indicators was relatively high.Conclusion:QD immunoanalyzer QD-S1200 for pediatric infectious pneumonia is high,and the waiting time is shorter,and the comprehensive application value of clinical testing is high.