鸡蛋源纳米硫化亚铁的合成及其对尖孢镰刀菌引起的囊肿的治疗作用

Synthesis of Egg White-derived Nano-ferrous Sulfide and Its Therapeutic Effect on Cysts Caused by Fusarium oxysporum

在对1例犬右肺囊肿伴肝淤血和胃肠臌气诊治的基础上,分离鉴定出1株尖孢镰刀菌(Fusarium oxysporum),同时合成和探究鸡蛋源纳米硫化铁对尖孢镰刀菌引起的犬囊肿的治疗效果。通过病原学诊断、病史调查、临床表现、血液学生理生化指标检查、X线检查等方法诊断该病为尖孢镰刀菌引起的多器官囊肿。通过正交试验合成了抗真菌的鸡蛋源纳米硫化亚铁,并将其应用于抑制尖孢镰刀菌生长。结果表明:根据诊断结果采用对因治疗(鸡蛋源纳米硫化亚铁抗尖孢镰刀菌)和对症治疗(高压氧舱吸氧、肝肺和胃肠穿刺),达到了抗尖孢镰刀菌引起的囊肿的治疗效果。

Based on the diagnosis and treatment of a canine right lung cyst with liver congestion and gastrointestinal gas,a strain of Fusarium oxysporum was isolated and identified.At the same time,the therapeutic effect of egg white-derived nano-iron sulfide on canine cysts caused by Fusarium oxysporum was synthesized and explored.The disease was diagnosed as multiple organ cysts caused by Fusarium oxysporum by etiological diagnosis,medical history investigation,clinical manifestations,hematological physiological and biochemical index examination,X-ray examination and other methods.Antifungal egg white-derived nano-iron sulfide was synthesized by orthogonal test and applied to inhibit the growth of Fusarium oxysporum.The results showed that according to the diagnosis results,the therapeutic effect of anti-F.oxysporum cysts was achieved by treatment(egg white source nano-ferrous sulfide anti-F.oxysporum)and symptomatic treatment(hyperbaric oxygen chamber oxygen inhalation,liver and lung and gastrointestinal puncture).