基于瘀毒理论治疗恶性高血压继发血栓性微血管病肾损害经验

Experience in Treating Renal Damage of Secondary Thrombotic Microangiopathy of Malignant Hypertension Based on Stasis Toxin Theory

血栓性微血管病(TMA)是一组主要关于病理组织学的诊断,可见多器官微血管血栓阻塞导致功能衰竭,临床最常见的继发因素为恶性高血压。通过观察恶性高血压、TMA二者致病的临床症状及病理特点,运用中医瘀毒理论,遣方用药遵循化瘀毒之治则,兼顾补虚荡涤之法,使邪有可祛,并观察中医药在治疗恶性高血压、TMA上的特色优势,为临床实践提供经验。附验案1则佐证。

Thrombotic microangiopathy(TMA)is a group of diagnoses mainly related to histopathology.It can be seen that thrombus obstruction in multi-organ microvessels leads to functional failure,and the most common secondary factor is malignant hypertension.By observing the clinical symptoms and pathological characteristics caused by malignant hypertension and thrombotic microangiopathy,applying the stagnation-toxin theory of traditional Chinese medicine,the prescription medication should follow the treatment principle of removing stasis and poison,taking into account the method of tonifying deficiency and cleaning,and observing the characteristics and advantages of traditional Chinese medicine in the treatment of malignant hypertension and TMA,so as to provide experience for clinical practice.One case was attached.