疏肝调冲汤结合心理干预治疗肝郁化火型女性迟发性痤疮的临床疗效观察

Clinical effects of Shugan Tiaochong Decoction combined with psychological intervention in the treatment of female delayed acne vulgaris of liver depression fire type

目的:观察疏肝调冲汤结合心理干预在肝郁化火型女性迟发性痤疮(FDAV)治疗中的应用疗效。方法:选取皮肤科门诊诊治的80例FDAV病人,并将其按随机数字表法分成中药组(应用疏肝调冲汤治疗)和联合组(在中药组基础上实施心理治疗),各40例,疗程均为2个月。比较2组疗效、中医证候积分、皮损评分、生活质量、不良反应及复发情况。结果:联合组总有效率97.50%,较中药组的82.50%高(χ^(2)=5.00,P<0.05);治疗结束后,2组中医证候积分、皮损总分及皮肤病生活质量指数评分均低于入组时(P<0.05),且联合组较中药组低(P<0.01);联合组复发率5.13%,较中药组的24.24%低(χ^(2)=5.46,P<0.05)。结论:对肝郁化火型FDAV实施疏肝调冲汤结合心理干预的效果较佳,可明显改善病人症状及皮损,显著提高生活质量,有效降低复发率。

Objective:To observe the clinical effects of Shugan Tiaochong Decoction combined with psychological intervention in the treatment of female delayed acne vulgaris(FDAV)of liver depression fire type.Methods:A total of 80 FDAV patients from dermatology outpatient department were selected,and divided into the TCM group(treated with Shugan Tiaochong Decoction)and combined group(treated with psychotherapy on the basis of Chinese medicine group)according to random number table method(40 cases in each group).The course of treatment was 2 months.The efficacy,TCM syndrome score,skin lesion score,quality of life,adverse reactions and recurrence were compared between two groups.Results:The total effective rate of the combined group was 97.50%,which was higher than that of the TCM group(82.50%)(χ^(2)=5.00,P<0.05).After treatment,the TCM syndrome score,total skin lesion score and dermatological life quality index score in two groups were lower than those at the time of enrollment(P<0.05),and those in the combined group were lower than that in TCM group(P<0.01).The recurrence rate of the combined group was 5.13%,which was lower than that of TCM group(24.24%)(χ^(2)=5.46,P<0.05).Conclusions:The effects of Shugan Tiaochong Decoction combined with psychological intervention in the treatment of FDAV of liver depression fire type are better,which can significantly improve the symptoms,skin lesions and quality of life of patients,and effectively reduce the recurrence rate.