Effect of electroacupuncture combined with repetitive transcranial magnetic stimulation on limb dysfunction in patients with ischemic stroke

电针联合重复经颅磁刺激对缺血性中风患者肢体功能障碍的影响

(rTMS) on limb dysfunction in ischemic stroke patients. Methods: A total of 63 stroke patients were divided into an observation group and a control group using the random number table method. Thirty-one patients in the control group were treated with routine Western medicine combined with rTMS;32 patients in the observation group were treated with EA in addition to the intervention in the control group. The duration of treatment was 3 months. The National Institutes of Health stroke scale (NIHSS), the Fugl-Meyer assessment (FMA), the modified Barthel index (MBI), and the motor evoked potential (MEP) latency of transcranial magnetic stimulation were observed before and after treatment in both groups. Results: Two cases withdrew from the observation group and 1 case withdrew from the control group. After treatment, the NIHSS score in both groups was lower than that before treatment, the FMA and MBI scores were higher than those before treatment, and the latency period of MEP was shorter than that before treatment, and the differences were statistically significant (P<0.05). After treatment, the NIHSS, FMA, and MBI scores and MEP latency period of the observation group improved more than those of the control group, and the differences between the groups were statistically significant (P<0.05). Conclusion: EA combined with rTMS can improve the motor function of limbs in ischemic stroke patients and improve their self-care ability. The mechanism may be related to increasing the excitability of the motor cortex and improving the electrophysiological function of the central nervous system.

目的: 观察电针联合重复经颅磁刺激(rTMS)对缺血性中风患者肢体功能障碍的影响。方法: 将63例中风患者 以随机数字表法分为观察组和对照组。对照组31例给予常规西医联合rTMS治疗;观察组32例在对照组干预基础上 加用电针治疗。疗程均为3个月。观察两组治疗前后美国国立卫生院中风量表(NIHSS)、Fugl-Meyer评估(FMA)、改 良Barthel指数(MBI)及经颅磁刺激运动诱发电位(MEP)潜伏期。结果: 观察组脱落2例, 对照组脱落1例。治疗后两组 患者NIHSS评分均较治疗前降低, FMA及MBI评分均较治疗前增高, MEP潜伏期均较治疗前缩短, 差异均具有统计学意 义(P<0.05)。治疗后观察组NIHSS量表、FMA量表及MBI评分以及MEP潜伏期改善程度优于对照组, 组间差异具有统 计学意义(P<0.05)。结论: 电针联合rTMS治疗可改善缺血性中风患者肢体运动功能, 提高生活自理能力。其机制可 能与提高运动皮质兴奋性, 改善中枢神经电生理功能相关。