摘要
As a traditional Chinese herbal medicine component,Corydalis yanhusuo is gradually attracting the attention of the skin care industry.In this study,Corydalis yanhusuo root extract dispersion(CTR50)was used as the research object.The related activities of Corydalis yanhusuo root extract dispersion were studied by cytotoxicity test,in vitro and in vivo antioxidant test and cell scratch healing test.The results showed that the dispersion of Corydalis yanhusuo root extract had no cytotoxicity to HaCaT cells.When the concentration of Corydalis yanhusuo root extract dispersion was 5%,the scavenging rate of DPPH free radical was 35.05%,and the scavenging ability of hydroxyl radical was weak;CTR50 can significantly increase the activity of SOD in HaCaT cells,increase the content of antioxidant factor GSH in HaCaT cells induced by UVB,and improve the oxidative stability of skin;it significantly promoted the healing ability of HaCaT cells at the scratch site.It can be seen that the dispersion of Corydalis yanhusuo root extract has the potential to be used as a functional raw material for natural skin care products,which provides a theoretical basis for its development and application in the field of cosmetics.
