摘要
目的探讨基于知识转化(KTA)模式的术前疼痛管理对胃肠癌患者术后疼痛程度、认知功能和炎症反应水平的影响。方法选取2022年3月至2023年3月在中山市人民医院进行肿瘤切除术治疗的92例胃肠癌患者为研究对象,采用随机数表法分为两组,每组各46例。对照组术前给予常规疼痛管理,观察组术前给予基于KTA模式的疼痛管理,比较两组患者疼痛程度、炎症因子水平、认知功能以及护理满意度评分。结果术后24 h,观察组患者视觉模拟评分法评分低于对照组,差异有统计学意义(P<0.05);术后24 h,观察组患者血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平均显著低于对照组,差异有统计学意义(P<0.05);术后1周,两组患者蒙特利尔认知评估量表(MoCA)总分均较术后当天显著升高,且观察组患者MoCA总分高于对照组,差异有统计学意义(P<0.05);观察组护理满意度高于对照组,差异有统计学意义(P<0.05)。结论采取基于KTA模式的术前疼痛管理可有效改善患者术后的疼痛程度、减轻炎症反应以及提高患者认知功能,值得临床应用。
Objective To explore the impact of preoperative pain treatment based on knowledge to action framework(KTA)model on postoperative pain level,cognitive function level and inflammatory response level of patients with gastrointestinal cancer.Methods A total of 92 patients with gastrointestinal cancer who underwent tumor resection treatment in Zhongshan People’s Hospital from March 2022 to March 2023 were selected for the study,and were divided into two groups using the random number table method,with 46 cases in each group.The control group was given conventional pain management before surgery,and the observation group was given pain management based on the KTA model before surgery,comparing the pain level,inflammatory factor level,cognitive function,and nursing satisfaction scores of patients in the two groups.Results At 24 h postoperatively,the visual analogue scale score of patients in the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).At 24 h postoperatively,serum interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)levels of patients in the observation group were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).1 week after the operation,the total scores of Montreal cognitive assessment scale(MoCA)of patients in both groups were significantly higher than that on the day after the operation,and the total scores of MoCA of patients in the observation group were higher than that of the control group,and the difference was statistically significant(P<0.05).The nursing care satisfaction of the observation group was higher than that of the control group,with a statistically significant difference(P<0.05).Conclusion The preoperative pain treatment based on KTA model can effectively improve patients’postoperative pain level,reduce inflammatory response,and improve patients’cognitive function,which is worthy of clinical application.
作者
余璐萍
邓爱爱
文洁
方艳霞
蔡莹莹
YU Luping;DENG Aiai;WEN Jie;FANG Yanxia;CAI Yingying(DepartmentⅡof Orthopedics,Zhongshan People’s Hospital,Guangdong,Zhongshan 528403,China)
出处
《中国医药科学》
2024年第22期90-93,共4页
China Medicine And Pharmacy
基金
广东省中山市卫生健康局医学科研项目(2021J092)。
关键词
KTA模式
疼痛管理
胃肠癌
认知功能
炎症因子
KTA mode
Pain treatment
Gastrointestinal cancer
Cognitive function
Inflammatory factor