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丹参酮ⅡA治疗心力衰竭的文献计量学分析

A bibliometric analysis of treating heart failure with tanshinone IIA
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摘要 目的:了解近20年来丹参酮ⅡA治疗心力衰竭研究领域的科学产出特点、研究热点和研究前沿,为今后该领域的研究者和研究机构提供一定的方向性参考。方法:检索并筛选2003年1月1日-2023年12月30日收录于中国知网知识服务平台、中文科技期刊数据库和万方数据知识服务平台中关于丹参酮ⅡA治疗心力衰竭的文献,使用COOC 12.8、Vosview 1.6.18、CiteSpace 6.2.R6软件对该研究领域的研究科学产出、研究热点和研究前沿进行可视化分析。结果:丹参酮ⅡA治疗心力衰竭研究领域相关文献整体产出呈波浪式发展,《中草药》杂志的发文量稳居首位,国家自然科学基金为该领域的研究提供了有力支持,蔡辉、赵智明、常文静、赵凌杰、董晓蕾等作者在该领域发文量和合作较多,研究机构中南京军区南京总医院中西医结合科发文量最多,郑州大学第一附属医院药学部不仅发文量较大,与各机构间的合作也较多,在该研究领域占有重要地位。研究热点包括心力衰竭相关疾病、中药及中药复方相关成分测定及测定方法、相关作用机制的信号通路、观察指标选择及试验方法等方面,研究前沿主要为“信号通路”“分子对接”“指纹图谱”“作用机制”“心肌梗死”“氧化应激”等。结论:丹参酮ⅡA治疗心力衰竭的研究有一定基础,近年来该领域研究的深度进一步深化,应以前期研究为基础,将临床与实验相结合,广大研究者积极参与,明确作用机制的信号通路,精准联合用药,以服务于临床,提高患者的生活质量。 Objective:To understand the scientific output characteristics,research hotspots,and research frontiers in the field of treating heart failure with tanshinoneⅡA over the past 20 years,so as to provide directional references for researchers and research institutions in this field in the future.Methods:The literature on treating heart failure with tanshinoneⅡA was retrieved and screened out from CNKI,Chinese Science and Technology Periodical Database,and Wanfang Data from January 1,2003 to December 30,2023.The visual analyses of scientific output,research hotspots,and research frontiers in this research field were performed by COOC 12.8,Vosview 1.6.18,and CiteSpace 6.2.R6.Results:The overall output of relevant literature in the field of treating heart failure with tanshinoneⅡA showed a wave-like development trend.Chinese Herbal Medicine,ranked first in the number of publications.The National Natural Science Foundation provided strong support for research in this field.Authors such as CAI Hui,ZHAO Zhiming,CHANG Wenjing,ZHAO Lingjie,and DONG Xiaolei had higher publication outputs and collaboration in this field.Among the research institutions,the Department of Integrated Traditional and Western Medicine of Nanjing General Hospital of Nanjing Military Region had the highest publication output;the Pharmacy Department of the First Affiliated Hospital of Zhengzhou University not only had higher publication output but also had more collaborations with other institutions,occupying an important position in this research field.Research hotspots included diseases related to heart failure,components determination and determination methods of Chinese medicine and Chinese medicine compound,signaling pathways of related action mechanisms,selection of observation indicators,trial methods,etc..The research frontiers were mainly signaling pathways,molecular docking,fingerprinting,action mechanisms,myocardial infarction,and oxidative stress.Conclusion:Research on the treatment of heart failure with tanshinoneⅡA has a certain foundation.In recent years,the research in this field has been further deepened.Based on previous research,clinical and experimental approaches should be combined,and researchers should actively participate to clarify the signaling pathways of action mechanism to perform precise combined medication,so as to serve clinical practice,thereby ameliorating the quality of life of patients.
作者 王庆胜 于小刚 辛二旦 WANG Qingsheng
出处 《中医临床研究》 2024年第31期104-109,共6页 Clinical Journal Of Chinese Medicine
基金 国家中医药管理局:国中医药人教函[2022]239号 甘肃省中医药研究中心2020年专项开放课题(zyzx-2020-zx25) 甘肃中医药大学附属医院科研及技术创新基金(gzfy-2021-09) 甘肃省名中医传承工作室建设项目(甘中医药发【2024】7号) 甘肃省中医药科研课题(GZKG-2024-48)。
关键词 丹参酮ⅡA 心力衰竭 研究现状 研究前沿 文献计量学 TanshinoneⅡA Heart failure Research status Research frontier Bibliometrics
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