摘要
目的分析糖肾康煎剂治疗糖尿病肾病患者的应用效果。方法选取2022年3月—2024年2月陕西糖尿病医院收治的100例糖尿病肾病患者为研究对象,按照治疗方法的不同分为两组,各50例。对照组行西医治疗,研究组行西医+糖肾康煎剂治疗。比较两组临床疗效、中医证候积分、血糖水平、肾功能、脂代谢指标及不良反应发生情况。结果研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组神疲乏力积分、肢体麻木积分、腰膝酸软积分、空腹血糖、餐后2 h血糖、尿素氮、血肌酐、尿微量白蛋白排泄率、总胆固醇、甘油三酯水平均低于对照组,高密度脂蛋白胆固醇水平高于对照组,差异均有统计学意义(P均<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论糖尿病肾病西医治疗中加用糖肾康煎剂,可改善患者血糖和脂代谢指标,改善临床症状,保护肾功能,提高临床疗效。
Objective To analyze the application effect of Tangshenkang Decoction in the treatment of patients with diabetic nephropathy.Methods A total of 100 patients with diabetic nephropathy admitted to Shaanxi Diabetes Hospital from March 2022 to February 2024 were selected as the research objects and divided into two groups according to different treatment methods,with 50 cases in each group.The control group was treated with Western medicine,and the study group was treated with Western medicine+Tangshenkang Decoction.The clinical efficacy,traditional Chinese medicine syndrome score,blood glucose level,renal function,lipid metabolism index and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of mental fatigue,limb numbness,waist and knee weakness,the levels of fasting blood glucose,2-hour postprandial blood glucose,urea nitrogen,serum creatinine,urinary microalbumin excretion rate,total cholesterol and triglyceride in the study group were lower than those in the control group,and the level of high-density lipoprotein cholesterol was higher than that in the control group,the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The addition of Tangshenkang Decoction to the Western medicine treatment of diabetic nephropathy can improve the blood glucose and lipid metabolism indexes of patients,improve clinical symptoms,protect renal function and improve clinical efficacy.
作者
罗燕丽
杨昭
赵永铭
LUO Yanli;YANG Zhao;ZHAO Yongming(Department of Traditional Chinese Medicine,Shaanxi Diabetes Hospital,Xi'an 710000,Shaanxi,China)
出处
《糖尿病新世界》
2024年第20期150-153,共4页
Diabetes New World
关键词
糖尿病肾病
糖肾康煎剂
肾功能
Diabetes nephropathy
Tangshenkang Decoction
Renal function