摘要
皂苷是苷元为三萜或螺旋甾烷类化合物的一类糖苷,它为一种常见的活性成分,具有很重要的营养价值,如抑菌、抗肿瘤、降血糖、调节肠道菌群。同时,皂苷也存在很多局限性,如溶血性、器官毒性,生物利用度低,组织刺激性强,这极大地限制了皂苷在功能食品上的应用。目前通过一些方法来改善这些问题。本文综述近年来常见植物源皂苷的研究进展,基于其分类与结构解析,介绍其生理活性,临床应用的局限性及其解决措施,旨在为植物源皂苷在疾病预防与治疗中的应用提供理论依据。
Saponins are a class of glycosides in which aglycones are triterpenoids or spiral steranes.They are regarded as common active ingredients and have important nutritional value,such as bacteriostasis,anti-tumor,hypoglycemic,and regulation of intestinal flora.At the same time,saponins also have many limitations,such as hemolysis,organ toxicity,low bioavailability,strong tissue irritation,which greatly limits the application of saponins in functional foods.At present,some methods are used to improve these problems.This paper reviewed the research progress of common plant-derived saponins in recent years.Based on their classification and structural analysis,this paper introduced their physiological activities,limitations of clinical application and solutions,aiming to provide theoretical basis for the application of plant-derived saponins in disease prevention and treatment.
作者
郝蓓琼
曹艳
刘晨星
李永新
夏其乐
Hao Beiqiong;Cao Yan;Liu Chenxing;Li Yongxin;Xia Qile(School of Food and Health,Zhejiang Agriculture and Forestry University,Hangzhou 311300;Institute of Food Science,Zhejiang Academy of Agricultural Sciences,Key Laboratory of Postharvest Handling of Fruits,Ministry of Agriculture and Rural Affairs,Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province,Key Laboratory of Postharvest Preservation and Processing of Vegetables(Co-construction by Ministry and Province),Ministry of Agriculture and Rural Affairs,Hangzhou 310021)
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2024年第11期459-471,共13页
Journal of Chinese Institute Of Food Science and Technology
基金
浙江省重点研发领雁项目(2023C04027)
浙江省三农九方项目(2023SNJF028,2023SNJF016)。
关键词
植物源皂苷
结构分类
生理活性
应用局限
解决措施
plant-derived saponins
structural classification
physiological activity
application limitations
solutions