生物可降解聚(乳酸-碳酸酯)材料研究进展

Progress on Research of Biodegradable Poly(lactic acid-carbonate)Materials

聚乳酸和脂肪族聚碳酸酯是具有绿色、无毒、无污染等特点的生物可降解材料,但是这2种材料在热性能、力学性能等方面存在一定不足,限制了它们的进一步应用。通过将二者共聚合成聚(乳酸-碳酸酯)材料是对其进行改性的有效途径。共聚改性可显著改善材料各项性能,进一步扩展它们的应用范围。本文综述了近年来聚(乳酸-碳酸酯)材料的相关研究成果,包括CO_(2)/环氧化物/丙交酯共聚法、丙交酯/环状碳酸酯开环共聚法及扩链法等3种合成方法,以及共聚物在形状记忆聚合物、弹性体、微球和支架材料等不同方面的应用,并对未来的发展前景进行了展望。

Polylactic acid and aliphatic polycarbonate are biodegradable materials with green,non-toxic,and pollution-free characteristics.However,these two materials have certain shortcomings in thermal and mechanical properties,which limit their further application.Copolymerization of the two to synthesize bio-based poly(lactic acid-carbonate)materials is an effective way to modify them.Copolymerization modification can significantly improve the various properties of the materials and further expand their application scope.This article reviewed the relevant research results of poly(lactic acid-carbonate)materials in recent years,including three synthesis methods:CO_(2)/epoxide/lactide copolymerization,lactide/cyclic carbonate ring opening copolymerization,and chain extension method.The applications of copolymers in shape memory polymers,elastomers,microspheres,and scaffold materials were discussed,and the future development prospects were envisaged.