摘要
肝细胞癌(hepatocellular carcinoma,HCC)是全球发病率最高的恶性肿瘤之一,且HCC早期临床表现不明显,多数患者在出现症状和体征时,已经到了中晚期且失去手术的机会;即使部分患者进行了手术治疗,术后复发较早,预后较差,后续治疗手段有限都导致了HCC高致死率。随着人们对HCC认识的加深及对其防治的重视,近年来出现了大量针对HCC的预测模型。该综述就目前HCC预测模型研究现状进行讨论,旨在比较目前认可度较高的一些预测模型的优劣以及应用范围并进一步促进其在临床中的应用。
Hepatocellular carcinoma(HCC)is a prevalent global malignancy characterized by inconspicuous early clinical manifestations;the majority of patients have already progressed to an advanced stage by the time symptoms and signs become apparent,thereby missing the opportunity for surgical intervention.Despite surgical interventions,early recurrence and unfavorable prognoses are common,while subsequent treatment options remain limited,contributing to an elevated HCC-associated mortality rate.The increasing awareness and emphasis on HCC prevention and treatment have stimulated the development of numerous predictive models in recent years.This review aims to discuss the current state of research on HCC predictive models,comparing the strengths and limitations of widely recognized models,and evaluating their applicability in clinical settings with an ultimate goal of promoting their integration into clinical practice for improved outcomes in managing HCC.
作者
邓航
张浩
DENG Hang;ZHANG Hao(School of Medicine,University of Electronic Science and Technology of China,Chengdu 610057,Sichuan,China;不详)
出处
《实用医学杂志》
CAS
北大核心
2024年第24期3561-3567,共7页
The Journal of Practical Medicine
基金
四川省科学技术厅重点研发项目(编号:2022YFS0092)。
关键词
肝细胞癌
早期诊断
预测模型
预后
hepatocellular carcinoma
early diagnosis
predictive models
prognosis