摘要
目的建立基于灰色关联结合秩和比法的药品不良反应(ADR)报告质量评价模型,为ADR报告质量的合理评价提供参考。方法参照相关规定和标准,用灰色关联与秩和比相结合的方法,对某市2022年上报至国家药品不良事件监测信息系统的ADR原始报告质量进行研究评价。结果15.4%的报告质量为中等(r(i)>0.7326);74.6%的报告质量为合格(0.6890<r(i)≤0.7326);1%的报告质量较差(r(i)≤0.6890),报告存在的主要问题包括ADR名称规范性欠佳、用药原因缺失、ADR分析不全面等。结论灰色关联度结合秩和比的方法用于评价ADR报告质量,能综合两种方法的优势、使结果更为合理。
Objective To develope a quality evaluation model for adverse drug reaction(ADR)re-ports based on a combination of Grey Relational Analysis and Rank-Sum Ratio methods,witch can provid a reference for reasonable assessment of ADR report quality.Methods evaluating the quality of ADR original reports submitted to the National Adverse Drug Event Monitoring Infor-mation System from a certain city in 2022,followed relevant regulations and standards and used a combination of Grey Relational Analysis and Rank-Sum Ratio methods.Results 15.4%of the reports had medium quality(r(i)>0.7326);74.6%had acceptable quality(0.6890<r(i)≤0.7326);and 1%had poor quality(r(i)≤0.6890).Main issues included inadequate standardi-zation of ADR names,missing medication reasons,and incomplete ADR analysis.Conclusion Combining Grey Relational Analysis with Rank-Sum Ratio methods to evaluat ADR report quali-ty effectively integrates the advantages of both methods,resulting in a more reasonable outcome.
作者
秦海钰
董斌
王红红
庞文娟
陈荣红
Qin Haiyu;Dong Bin;Wang Honghong;Pang Wenjuan;Chen Ronghong(Wuwei Drug Inspection and Testing Center,Gansu 733000,China)
出处
《青岛医药卫生》
2024年第5期345-350,共6页
Qingdao Medical Journal
基金
武威市市级项目(WW23B02SF088、WW24B01GY006、WW24B01GY005、WW24B01NY052)。
关键词
药品不良反应
报告质量
灰色关联度法
秩和比法
Adverse Drug Reactions
Report Quality
Grey Relational Analysis
Rank-Sum Ratio