摘要
Prediabetes is a heterogeneous condition,encompassing various pathological phenotypes such as hyperinsulinemia,tissue-specific insulin resistance(IR),systemic IR,andβ-cell dysfunction.A significant proportion of individuals with prediabetes remain undiagnosed.Furthermore,although lifestyle interventions have demonstrated efficacy in improving prediabetic conditions,some individuals with prediabetes progress to type 2 diabetes mellitus.This study aims to summarize effective evaluation methods for identifying distinct pathological phenotypes of prediabetes and targeted lifestyle intervention strategies to mitigate the progression from prediabetes to diabetes.