羟基磷灰石涂层人工关节应用研究

Investigation on Artificial Joint Coated by Hydroxyapatite

对羟基磷灰石的成骨效应进行了研究 ,对添加骨水泥不当而导致的羟基磷灰石涂层人工关节涂层脱落进行了分析。结果表明 ,对于羟基磷灰石涂层人工关节 ,应有涂层区和非涂层区 ,骨水泥只能在非涂层区填充 ,而在涂层区则应使羟基磷灰石涂层直接与骨组织接触。这种人工关节 ,不仅充分利用了羟基磷灰石良好的生物相容性和成骨效应 。

The effect of hydroxyapatite on bone growth was studied. The cause of hydroxyapatite coating drop out from artificial joint resulted by bone cement improperly filling was analyzed. The results show that both coating zone and non-coating zone are needed on artificial joint. The bone cement should be only filled into non-coating zone. On the coating zone, the hydroxyapatite coating need to closed coat on bone structure. The artificial joint containing of coating zone and non-coating zone is not only utilizing the biological fixation and effect on bone growth of hydroxyapatite, but also favor to temporary mechanical fixation and long time biological fixation after operation.