日本血吸虫病患者血清TNF-α、IL-1β和NO水平检测

Detection of TNF-α,IL-1β and NO in sera of patients with schistosomiasis japonicum

目的 检测日本血吸虫病患者血清TNF α、IL 1β和NO水平。 方法 分别收集 2 0例日本血吸虫病患者和健康志愿者血清 ,用试剂盒分别检测血清TNF α、IL 1β和NO水平。 结果 日本血吸虫病患者血清TNF α、IL 1β和NO水平显著升高。结论 TNF α、IL 1β和NO可能在宿主杀伤日本血吸虫童虫和形成虫卵肉芽肿方面起重要作用。

Objective To detect TNF α,IL 1β and NO in sera of patients with schistosomiasis japonicum. Methods 20 sera of patients with schistosomiasis japonicum and health volunteers were gathered respectively to detect levels of TNF α,IL 1β and NO by kits respectively. Results TNF α,IL 1β and NO obviouisly increased in sera of patients with schistosomiasis japonicum. Conclusion TNF α,IL 1βand NO may play important roles in killing schistosomula of Schistosoma japonicum and forming egg granulomas.