从微循环角度诊治胸外伤性ARDS患者的临床研究

The Clinical Study of The Diagnosis and Treatment of The Patients Suffering From Post Thoracic Trauma Ards From The Angle of Microcirculation

目的 探讨成人呼吸窘迫综合征 (ARDS)的有效治疗措施。方法 将已确诊为胸外伤性ARDS的患者随机地为两组 ,分别交替进行东莨菪碱为主的综合治疗的实验组和综合治疗的对照组。结果 实验组治愈率 (2 3 2 6 )明显好于对照组 (13 2 0 ) ;对ARDS患者来说 ,应用东莨菪碱治疗越早越好 ,剂量必须达“莨菪化”和“个体化” ;患者症状体征改善后应逐渐停药 ,必要时行气管切开术。

Objective To discuss the effect of scopolamine in treating the microcirculation disturbance from these angles of Pharmacology, Physiology and Pathophysiology.Methods 46 patients diagnosed as post thoracic trauma (ARDS) were divided at random into two groups, treated either with combined treatment (Group B) or mainly with scopolamine (Group A). Results The result suggested that the curative rate of Group A (23/26) is obviously better than that of Group B (13/20).It is better to give scopolamine as early as possible, and full-dose must be attained. After remission, its dosage should be reduced stepwise. Sometimes tracheostomy must be performed. Conclusions Scopo lamine has strong effecf in treating ARDS.