慢性胰腺炎的实验室检查分析

Laboratory profiles of chronic pancreatitis

目的 :提高慢性胰腺炎的诊断水平。方法 :回顾性分析 1993～ 2 0 0 0年 88例慢性胰腺炎患者有关实验室检查的结果和意义。结果 :84%(4 2 / 5 0 )尿N 苯甲酰 L 酪氨酰 对氨苯甲酸 (N benzoyl L tyrosyl p aminobenzoicacid ,BT PABA)试验阳性。 73 3%(2 2 / 30 )粪便苏丹Ⅲ染色阳性。 83 3%(5 / 6 ) 2 4h粪便脂肪定量阳性。 80 %(8/ 10 )粪便弹力蛋白酶试验阳性。 2 6 5 %(18/ 6 8)血淀粉酶升高。 2 4 3%(7/ 2 9)血CA19 9升高。结论 :慢性胰腺炎患者尿BT PABA试验的阳性率较其他检查略高。对于慢性胰腺炎的诊断需要结合多种检查 ,综合分析 ,尽早诊断。

Objective:To raise the diagnosing efficiency in chronic pancreatitis. Methods: The clinical feature and laboratory data of 88 cases of chronic pancreatitis from 1993 to 2000 were analysed retrospectively. Results: In 88 cases of chronic pancreatitis, the positive rate of the urine N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BT-PABA) test was 84% (42/50), which of the fecal Sudan test was 73.3% (22/30). 5 of 6 cases (83.3%) 24 hours quantitative test of fecal fat was positive, and 8 of 10 cases (80%) the fecal elastase test was positive. The rate of blood amylase elevation was 26.5%. The elevation rate of serum CA19-9 was 24.3%. Conclusion: The urine BT-PABA test is more effectual than other tests in diagnosis of chronic pancreatitis. It is necessary to analyse the data in combination of many tests in early diagnosis of chronic pancreatitis.