中重度下尿路症状患者的勃起功能障碍的研究

Erectile Dysfunction in Men with Moderate and Severe Lower Urinary Tract Symptoms

目的 评价伴有中重度下尿路症状的BPH患者中治疗前勃起功能障碍的程度。方法 本组 14 0例具有典型的下尿路症状的良性前列腺增生症患者。所有患者均进行了国际前列腺症状评分 (IPSS) ,且症状评分均在 8分以上。同时进行了勃起功能国际问卷表 (IIEF - 5 )调查 ,并以评分≤ 2 1诊断勃起功能障碍 ,>2 1诊断无勃起功能障碍。应用回归分析评价年龄、总IPSS评分、中重度IPSS评分与勃起功能评分的相关性。结果 本组患者年龄 5 4～ 83岁 ,平均 (6 9 2± 7 18)岁。IPSS评分 8～ 34分 ,平均 (2 3 3± 7 7)分 ,其中中度症状评分 (8～ 19分 )患者 4 5例 (32 % ) ,重度症状评分 (2 0～ 35 )分患者 95例 (6 8% )。IIEF - 5评分 0～ 2 5分 ,平均 (6 8± 8 0 2 )分 ,其中无勃起功能障碍患者 11例 (7 9% ) ,有勃起功能障碍患者 12 9例 (92 1% )。中、重度症状评分患者勃起功能障碍的发生率分别为 4 1例 (91% )和 88例 (93 6 % )。回归分析表明 :年龄与IIEF - 5问卷表无明显相关性 (γ =0 4 17)。IIPSS总评分与IIEF - 5问卷表无明显相关性 (γ =0 2 35 )。其中中度症状评分与IIEF问卷表无明显相关性 (γ =0 0 7) ,重度症状评分也无明显相关性 (γ =0 332 )。结论 本研究结果表明 90

Objective To evaluate the degree of erectile dysfunction in the benign prostate hyperplasia (BPH) of men with moderate and severe lower urinary tract symptoms (LUTS) .Methods Total 140 patients with moderate and severe LUTS of BPH were investigated using the International Prostate Symptom Score (IPSS) and International Index of Erectile Function-5 (IIEF-5). Erectile dysfunction was less than 21 scores, but erection was more than 21 scores. Regression analysis was used to determine the degree of any correlation among age, the total IPSS, the moderate and severe IPSS score and the various erectile function scores.Results The mean age of the patients was (69 2±7 18) years. The mean total IPSS score was 23 3±7 7, consisting of 45 patients (32%) for moderate IPSS score and 95 patients (68%) for severe IPSS score. The mean IIEF-5 score was 6 8±8 02. There were erection patients in 11 cases (7 9%) and erectile dysfunction patients in 129 cases (92 1%). On the other hand, 41 cases (91%) for moderate IPSS score and 88 cases (93 6%) for severe IPSS score exists erectile dysfunction. There were no significant correlation among IIEF-5 score and patients age (γ=0 417), the total IPSS (γ=0 235), the moderate (γ=0 07) and severe IPSS score (γ=0 332). Conclusions About 90% BPH men complicated with LUTS have erectile dysfunction. Erectile dysfunction is related to age and the extent of LUTS. LUTS is not an important factor of erectile dysfunction. The high morbidity of erectile dysfunction in BPH men with LUTS should be consider in the treatment of their urinary symptoms.